Indocyanine Green Brand Name– IC Green
What is Indocyanine Green
Indocyanine green is a parenteral tricarbocyanine dye and optical imaging agent indicated for determining cardiac output, hepatic function and liver blood flow, for ophthalmic angiography, and for visualization of extrahepatic biliary ducts, lymph nodes and lymphatic vessels in setting of cervical and uterine tumors, and vessels, blood flow, and tissue perfusion around several surgical procedures.
Severe hypersensitivity reactions, including deaths due to anaphylaxis, have been associated with intravenous administration the indocyanine green; cardiopulmonary resuscitation personnel and equipment must be readily available.
Indications
- angiography
- cardiac function diagnosis
- hepatobiliary system dysfunction diagnosis
- sentinel lymph node mapping
For use as an aid in cardiac function diagnosis
for determining cardiac output using indicator-dilution studies
Side Effects
- agitation
- anaphylactic shock
- anaphylactoid reactions
- anxiety
- bronchospasm
- cardiac arrest
- confusion
- cough
- cyanosis
- diaphoresis
- dyspnea
- edema
- erythema
- flushing
- headache
- hypotension
- laryngospasm
- nausea
- palpitations
- peripheral vasodilation
- pharyngitis
- pruritus
- respiratory arrest
- sinus tachycardia
- skin discoloration
- syncope
- urticaria
- visual impairment
- vomiting
- weakness
- wheezing
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- dialysis
- iodine hypersensitivity
- laboratory test interference
- pregnancy
- renal failure
- uremia
Interactions
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Haloperidol
- Heparin
- Hydrochlorothiazide, HCTZ; Propranolol
- Nifedipine
- Nitrofurantoin
- Phenobarbital
- Primidone
- Propranolol