Hydrocodone bitartrate Ibuprofen

Hydrocodone bitartrate Ibuprofen Brand Names- Ibudone | Reprexain | Vicoprofen | Xylon 10

What is Hydrocodone Ibuprofen

Hydrocodone bitartrate and ibuprofen are used together for the relief of acute pain. Hydrocodone is a semisynthetic opioid analgesic and antitussive. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects.

All NSAIDs carry an increased risk of serious gastrointestinal adverse effects including bleeding, ulceration, and perforation of the stomach or intestines and may cause an increased risk of serious cardiovascular (CV) thrombotic events, myocardial infarction, and stroke.

The lowest effective ibuprofen dose for the shortest possible duration is recommended, as the risk for adverse effects may increase with duration of use.

The American Geriatrics Society recommends that NSAIDs (nonselective and COX-2 inhibitors) not be used to treat persistent pain in elderly patients except rarely, then only in patients who have failed other therapies and have a favorable benefits vs. risks assessment; extreme caution, continued therapy evaluation, and concurrent PPI or misoprostol is advised with ibuprofen use in this population.

In clinical trials, one tablet of the combination of hydrocodone and ibuprofen was as effective as two tablets of Tylenol No. 3 (acetaminophen 300 mg and codeine phosphate 30 mg) in relieving acute pain resulting from sprains/strains, surgery, back disorders, dental procedures, sport injuries, and fractures/dislocations.

The FDA approved hydrocodone; ibuprofen (Vicoprofen) 7.5 mg/200 mg tablets in October 1997, hydrocodone; ibuprofen 5 mg/200 mg tablets (Reprexain) in March 2004, hydrocodone; ibuprofen 2.5 mg/200 mg tablets (Reprexain) in October 2007, and hydrocodone; ibuprofen 10 mg/200 mg tablets (Ibudone) in January 2008.

Indications

  • severe pain

For the treatment of short-term (generally less than 10 days) acute, severe pain that requires and opioid analgesic and for which alternative treatments are inadequate

Side Effects

  1. abdominal pain
  2. adrenocortical insufficiency
  3. agitation
  4. agranulocytosis
  5. amenorrhea
  6. angioedema
  7. anorexia
  8. anxiety
  9. aplastic anemia
  10. arthralgia
  11. aseptic meningitis
  12. asthenia
  13. biliary obstruction
  14. bleeding
  15. blurred vision
  16. bradycardia
  17. bullous rash
  18. confusion
  19. constipation
  20. cystitis
  21. depression
  22. diarrhea
  23. dizziness
  24. drowsiness
  25. dysgeusia
  26. dyspepsia
  27. dysphagia
  28. dyspnea
  29. edema
  30. elevated hepatic enzymes
  31. esophagitis
  32. euphoria
  33. exfoliative dermatitis
  34. fever
  35. flatulence
  36. flushing
  37. gastritis
  38. GI bleeding
  39. GI obstruction
  40. GI perforation
  41. glossitis
  42. glycosuria
  43. gonadal suppression
  44. headache
  45. heart failure
  46. hemolytic anemia
  47. hepatic failure
  48. hepatic necrosis
  49. hepatitis
  50. hiccups
  51. hoarseness
  52. hypertension
  53. hypertonia
  54. hyponatremia
  55. hypotension
  56. impotence (erectile dysfunction)
  57. infection
  58. infertility
  59. interstitial nephritis
  60. jaundice
  61. libido decrease
  62. maculopapular rash
  63. melena
  64. miosis
  65. myalgia
  66. myocardial infarction
  67. nausea
  68. neonatal opioid withdrawal syndrome
  69. nephrotic syndrome
  70. neutropenia
  71. oral ulceration
  72. orthostatic hypotension
  73. palpitations
  74. pancreatitis
  75. pancytopenia
  76. paresthesias
  77. peptic ulcer
  78. pharyngitis
  79. photophobia
  80. photosensitivity
  81. physiological dependence
  82. platelet dysfunction
  83. pruritus
  84. psychological dependence
  85. pyrosis (heartburn)
  86. rash
  87. renal papillary necrosis
  88. respiratory depression
  89. rhinitis
  90. serotonin syndrome
  91. SIADH
  92. sinus tachycardia
  93. sinusitis
  94. Stevens-Johnson syndrome
  95. stroke
  96. syncope
  97. thrombocytopenia
  98. thromboembolism
  99. tinnitus
  100. toxic epidermal necrolysis
  101. tremor
  102. urinary incontinence
  103. urinary retention
  104. urticaria
  105. vasculitis
  106. vertigo
  107. visual impairment
  108. vomiting
  109. weight loss
  110. withdrawal
  111. xerophthalmia
  112. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • abrupt discontinuation
  • accidental exposure
  • acute myocardial infarction
  • adrenal insufficiency
  • alcoholism
  • anemia
  • angina
  • anticoagulant therapy
  • asthma
  • biliary tract disease
  • bladder obstruction
  • bone marrow suppression
  • breast-feeding
  • cardiac arrhythmias
  • cardiac disease
  • cardiomyopathy
  • chemotherapy
  • chronic obstructive pulmonary disease (COPD)
  • coadministration with other CNS depressants
  • coagulopathy
  • constipation
  • coronary artery bypass graft surgery (CABG)
  • coronary artery disease
  • corticosteroid therapy
  • dental disease
  • dental work
  • diabetes mellitus
  • diarrhea
  • driving or operating machinery
  • edema
  • geriatric
  • GI bleeding
  • GI disease
  • GI obstruction
  • GI perforation
  • head trauma
  • heart failure
  • hematological disease
  • hemophilia
  • hepatic disease
  • hypertension
  • hypothyroidism
  • ileus
  • immunosuppression
  • increased intracranial pressure
  • infection
  • infertility
  • inflammatory bowel disease
  • intramuscular injections
  • jaundice
  • labor
  • myocardial infarction
  • myxedema
  • nasal polyps
  • neonatal opioid withdrawal syndrome
  • neutropenia
  • NSAID hypersensitivity
  • obstetric delivery
  • oliguria
  • opiate agonist hypersensitivity
  • peptic ulcer disease
  • peripheral vascular disease
  • polysorbate 80 hypersensitivity
  • potential for overdose or poisoning
  • pregnancy
  • prostatic hypertrophy
  • pulmonary disease
  • renal disease
  • renal failure
  • renal impairment
  • reproductive risk
  • respiratory depression
  • respiratory insufficiency
  • salicylate hypersensitivity
  • seizure disorder
  • sepsis
  • status asthmaticus
  • stroke
  • substance abuse
  • surgery
  • systemic lupus erythematosus (SLE)
  • tachycardia
  • thrombocytopenia
  • thromboembolism
  • tobacco smoking
  • ulcerative colitis
  • urethral stricture
  • urinary retention
  • urticaria

Interactions

  • Abciximab
  • Abiraterone
  • Acebutolol
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Codeine
  • Acetaminophen; Dextromethorphan; Doxylamine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Diphenhydramine
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Tramadol
  • Acetohexamide
  • Acrivastine; Pseudoephedrine
  • Acyclovir
  • Adefovir
  • Aldesleukin, IL-2
  • Alfentanil
  • Aliskiren
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Aliskiren; Valsartan
  • Almotriptan
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  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amobarbital
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  • Amoxicillin; Clarithromycin; Omeprazole
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  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
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  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril
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  • Bendamustine
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  • Benzhydrocodone; Acetaminophen
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  • Benzonatate
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  • Bisphosphonates
  • Bivalirudin
  • Bleomycin
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  • Brigatinib
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  • Brimonidine; Timolol
  • Brompheniramine
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  • Brompheniramine; Dextromethorphan; Guaifenesin
  • Brompheniramine; Dextromethorphan; Phenylephrine
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide
  • Budesonide; Formoterol
  • Bumetanide
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  • Bupivacaine Liposomal
  • Bupivacaine; Lidocaine
  • Buprenorphine
  • Buprenorphine; Naloxone
  • Bupropion
  • Bupropion; Naltrexone
  • Buspirone
  • Busulfan
  • Butabarbital
  • Butorphanol
  • Calcium Carbonate; Magnesium Hydroxide
  • Calcium Phosphate, Supersaturated
  • Calcium-channel blockers
  • Candesartan
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Cannabidiol
  • Capecitabine
  • Capreomycin
  • Capsaicin; Metaxalone
  • Captopril
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbamazepine
  • Carbetapentane; Chlorpheniramine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbinoxamine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Cariprazine
  • Carisoprodol
  • Carmustine, BCNU
  • Carteolol
  • Carvedilol
  • Castor Oil
  • Cefotaxime
  • Celecoxib
  • Cenobamate
  • Ceritinib
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexbrompheniramine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chloral Hydrate
  • Chlorambucil
  • Chloramphenicol
  • Chlorcyclizine
  • Chlordiazepoxide
  • Chlordiazepoxide; Clidinium
  • Chloroprocaine
  • Chlorothiazide
  • Chlorpheniramine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorpromazine
  • Chlorpropamide
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Chlorzoxazone
  • Cholestyramine
  • Choline Salicylate; Magnesium Salicylate
  • Cholinesterase inhibitors
  • Ciclesonide
  • Cidofovir
  • Cilostazol
  • Cimetidine
  • Cinacalcet
  • Ciprofloxacin
  • Citalopram
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  • Clofarabine
  • Clonazepam
  • Clonidine
  • Clopidogrel
  • Clorazepate
  • Clozapine
  • Cobicistat
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • Colchicine; Probenecid
  • Colistimethate, Colistin, Polymyxin E
  • COMT inhibitors
  • Conivaptan
  • Conjugated Estrogens; Bazedoxifene
  • Corticosteroids
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  • Crofelemer
  • Cyclizine
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  • Cyclosporine
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  • Cytarabine, ARA-C
  • Dabigatran
  • Dabrafenib
  • Dacarbazine, DTIC
  • Dacomitinib
  • Dactinomycin, Actinomycin D
  • Dalfopristin; Quinupristin
  • Dalteparin
  • Danaparoid
  • Danazol
  • Dantrolene
  • Darifenacin
  • Darunavir
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  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
  • Dasatinib
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  • Denileukin Diftitox
  • Desflurane
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  • Deutetrabenazine
  • Dexamethasone
  • Dexchlorpheniramine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmedetomidine
  • Dexpanthenol
  • Dextroamphetamine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Promethazine
  • Dextromethorphan; Quinidine
  • Diazepam
  • Diazoxide
  • Dichlorphenamide
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dicyclomine
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diltiazem
  • Dimenhydrinate
  • Diphenhydramine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dipyridamole
  • Docetaxel
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  • Donepezil
  • Donepezil; Memantine
  • Doravirine; Lamivudine; Tenofovir disoproxil fumarate
  • Dorzolamide; Timolol
  • Doxazosin
  • Doxylamine
  • Doxylamine; Pyridoxine
  • Dronabinol
  • Dronedarone
  • Droperidol
  • Drospirenone
  • Drospirenone; Estradiol
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Drotrecogin Alfa
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  • Elagolix
  • Elagolix; Estradiol; Norethindrone acetate
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  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Emtricitabine
  • Emtricitabine; Rilpivirine; Tenofovir alafenamide
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Emtricitabine; Tenofovir alafenamide
  • Emtricitabine; Tenofovir disoproxil fumarate
  • Enalapril, Enalaprilat
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  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enflurane
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  • food
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  • Gold
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  • grapefruit juice
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  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocortisone
  • Hydromorphone
  • Hydroxyzine
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
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  • Leflunomide
  • Lemborexant
  • Lepirudin
  • Lesinurad
  • Lesinurad; Allopurinol
  • Letermovir
  • Levobetaxolol
  • Levobunolol
  • Levobupivacaine
  • Levocetirizine
  • Levomefolate
  • Levomilnacipran
  • Levorphanol
  • Lidocaine
  • Lidocaine; Prilocaine
  • Lincosamides
  • Linezolid
  • Lisdexamfetamine
  • Lisinopril
  • Lithium
  • Lofexidine
  • Lomustine, CCNU
  • Loop diuretics
  • Loperamide
  • Loperamide; Simethicone
  • Lopinavir; Ritonavir
  • Lorazepam
  • Lorcaserin
  • Lorlatinib
  • Losartan
  • Loxapine
  • Lumacaftor; Ivacaftor
  • Lumacaftor; Ivacaftor
  • Lumateperone
  • Lurasidone
  • Macimorelin
  • Magnesium Citrate
  • Magnesium Hydroxide
  • Magnesium Salicylate
  • Magnesium Salts
  • Magnesium Sulfate; Potassium Sulfate; Sodium Sulfate
  • Mannitol
  • Maprotiline
  • Mecamylamine
  • Mechlorethamine, Nitrogen Mustard
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Melatonin
  • Meloxicam
  • Melphalan
  • Mepenzolate
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Mepivacaine
  • Mepivacaine; Levonordefrin
  • Meprobamate
  • Mesalamine, 5-ASA
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methocarbamol
  • Methohexital
  • Methotrexate
  • Methoxsalen
  • Methscopolamine
  • Methyclothiazide
  • Methyldopa
  • Methylene Blue
  • Methylphenidate
  • Methylprednisolone
  • Methylsulfonylmethane, MSM
  • Metoclopramide
  • Metolazone
  • Metoprolol
  • Metyrapone
  • Metyrosine
  • Midazolam
  • Mifepristone
  • Milnacipran
  • Mineral Oil
  • Minocycline
  • Minoxidil
  • Mirabegron
  • Mirtazapine
  • Mitomycin
  • Mitotane
  • Mitoxantrone
  • Modafinil
  • Moexipril
  • Molindone
  • Mometasone
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nabumetone
  • Nadolol
  • Nafcillin
  • Nalbuphine
  • Naloxone
  • Naltrexone
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Naratriptan
  • Nebivolol
  • Nebivolol; Valsartan
  • Nefazodone
  • Nelarabine
  • Nelfinavir
  • Neomycin
  • Neostigmine
  • Nesiritide, BNP
  • Netupitant, Fosnetupitant; Palonosetron
  • Nevirapine
  • Nicardipine
  • Nilotinib
  • Nitroglycerin
  • Nitroprusside
  • Non-Ionic Contrast Media
  • Olanzapine
  • Olmesartan
  • Omacetaxine
  • Ombitasvir; Paritaprevir; Ritonavir
  • Omeprazole; Amoxicillin; Rifabutin
  • Ondansetron
  • Oritavancin
  • Orphenadrine
  • Osilodrostat
  • Oxaprozin
  • Oxazepam
  • Oxcarbazepine
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Ozanimod
  • Paclitaxel
  • Palbociclib
  • Paliperidone
  • Palonosetron
  • Panobinostat
  • Papaverine
  • Paroxetine
  • Pazopanib
  • Pegaspargase
  • Peginterferon Alfa-2b
  • Pegvisomant
  • Pemetrexed
  • Penbutolol
  • Pentamidine
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentobarbital
  • Pentosan
  • Pentostatin
  • Perampanel
  • Perindopril
  • Perindopril; Amlodipine
  • Perphenazine
  • Perphenazine; Amitriptyline
  • Pexidartinib
  • Phenelzine
  • Phenobarbital
  • Phenoxybenzamine
  • Phentermine; Topiramate
  • Phentolamine
  • Phenylephrine; Promethazine
  • Phenytoin
  • Photosensitizing agents (topical)
  • Physostigmine
  • Pimozide
  • Pindolol
  • Piroxicam
  • Platelet Inhibitors
  • Pneumococcal Vaccine, Polyvalent
  • Polyethylene Glycol
  • Polyethylene Glycol; Electrolytes
  • Polyethylene Glycol; Electrolytes; Ascorbic Acid
  • Polyethylene Glycol; Electrolytes; Bisacodyl
  • Polymyxin B
  • Polymyxins
  • Posaconazole
  • Potassium
  • Pralatrexate
  • Pramipexole
  • Pramlintide
  • Prasugrel
  • Prazosin
  • Prednisolone
  • Prednisone
  • Pregabalin
  • Prilocaine
  • Prilocaine; Epinephrine
  • Primidone
  • Probenecid
  • Procaine
  • Procarbazine
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Propantheline
  • Propofol
  • Propoxyphene
  • Propranolol
  • Pyridostigmine
  • Quazepam
  • Quetiapine
  • Quinapril
  • Quinidine
  • Quinine
  • Quinolones
  • Ramelteon
  • Ramipril
  • Ranolazine
  • Rasagiline
  • Remifentanil
  • Reserpine
  • Reteplase, r-PA
  • Ribociclib
  • Ribociclib; Letrozole
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Rifaximin
  • Riluzole
  • Risperidone
  • Ritonavir
  • Rivaroxaban
  • Rivastigmine
  • Rizatriptan
  • Rolapitant
  • Romidepsin
  • Ropinirole
  • Ropivacaine
  • Rotigotine
  • Rucaparib
  • Sacubitril; Valsartan
  • Safinamide
  • Salicylates
  • Salsalate
  • Saquinavir
  • Scopolamine
  • Secobarbital
  • Selective serotonin reuptake inhibitors
  • Selegiline
  • Selpercatinib
  • Serotonin-Receptor Agonists
  • Serotonin-Receptor Antagonists
  • Sertraline
  • Sevoflurane
  • Sibutramine
  • Sildenafil
  • Simeprevir
  • Skeletal Muscle Relaxants
  • Sodium Hyaluronate, Hyaluronic Acid
  • Sodium Oxybate
  • Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
  • Sodium picosulfate; Magnesium oxide; Anhydrous citric acid
  • Solifenacin
  • Sorbitol
  • Sotalol
  • Spironolactone
  • St. John’s Wort, Hypericum perforatum
  • Streptogramins
  • Streptokinase
  • Streptomycin
  • Streptozocin
  • Sufentanil
  • Sulfinpyrazone
  • Sulfonylureas
  • Sulindac
  • Sumatriptan
  • Suvorexant
  • Tacrine
  • Tacrolimus
  • Tapentadol
  • Tasimelteon
  • Tazemetostat
  • Tedizolid
  • Telaprevir
  • Telavancin
  • Telbivudine
  • Telithromycin
  • Telmisartan
  • Telotristat Ethyl
  • Temazepam
  • Temozolomide
  • Tenecteplase
  • Teniposide
  • Tenofovir Alafenamide
  • Tenofovir, PMPA
  • Terazosin
  • Terbinafine
  • Tetrabenazine
  • Tetracaine
  • Tezacaftor; Ivacaftor
  • Thalidomide
  • Thiazide diuretics
  • Thioguanine, 6-TG
  • Thiopental
  • Thioridazine
  • Thiothixene
  • Thrombolytic Agents
  • Ticagrelor
  • Ticlopidine
  • Timolol
  • Tinzaparin
  • Tipranavir
  • Tirofiban
  • Tizanidine
  • tobacco
  • Tobramycin
  • Tolazamide
  • Tolbutamide
  • Tolmetin
  • Tolterodine
  • Topiramate
  • Torsemide
  • Tositumomab
  • Tramadol
  • Trandolapril
  • Trandolapril; Verapamil
  • Tranylcypromine
  • Trazodone
  • Treprostinil
  • Tretinoin, ATRA
  • Triamcinolone
  • Triamterene
  • Triazolam
  • Tricyclic antidepressants
  • Trifluoperazine
  • Trihexyphenidyl
  • Trimethobenzamide
  • Triprolidine
  • Trospium
  • Tucatinib
  • Urea
  • Urokinase
  • Valacyclovir
  • Valerian, Valeriana officinalis
  • Valganciclovir
  • Valproic Acid, Divalproex Sodium
  • Valsartan
  • Vancomycin
  • Vasodilators
  • Vemurafenib
  • Venlafaxine
  • Verapamil
  • Verteporfin
  • Vigabatrin
  • Vilazodone
  • Vincristine
  • Vincristine Liposomal
  • Vorapaxar
  • Voriconazole
  • Vorinostat
  • Vortioxetine
  • Voxelotor
  • Warfarin
  • Zafirlukast
  • Zaleplon
  • Ziconotide
  • Ziprasidone
  • Zolmitriptan
  • Zolpidem