Homatropine Hydrobromide Brand Name– Isopto Homatropine
What is Homatropine Hydrobromide
Homatropine hydrobromide is an ophthalmic, cycloplegic mydriatic agent. It is used for cycloplegic refraction and for dilating the pupil in inflammatory conditions of the uveal tract.
It is also used for pre- and postoperative mydriasis, iritis, ciliary spasm, as an aid in axial lens opacities and as a provocative agent in the diagnosis of open-angle glaucoma.
Homatropine is an inferior cycloplegic when compared to ophthalmic atropine or cyclopentolate, particularly in children.
Homatropine has a longer duration of action than tropicamide or cyclopentolate, but a shorter duration than atropine or scopolamine.
Homatropine hydrobromide was approved by the FDA pre-1938.
Indications
- cycloplegia induction
- iritis
- mydriasis induction
- uveitis
For mydriasis induction and cycloplegia induction for refraction
Side Effects
- agitation
- ataxia
- blurred vision
- bradycardia
- coma
- confusion
- conjunctivitis
- contact dermatitis
- cycloplegia
- delirium
- drowsiness
- dysarthria
- excitability
- fever
- flushing
- hallucinations
- mania
- mydriasis
- ocular hypertension
- ocular pain
- photophobia
- psychosis
- rash
- restlessness
- seizures
- sinus tachycardia
- urinary retention
- xerostomia
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- anticholinergic medications
- breast-feeding
- cardiac disease
- children
- closed-angle glaucoma
- contact lenses
- dementia
- driving or operating machinery
- gastroesophageal reflux disease (GERD)
- geriatric
- GI obstruction
- glaucoma
- hypertension
- ileus
- increased intraocular pressure
- infants
- neonates
- open-angle glaucoma
- pregnancy
- renal disease
- renal failure
- renal impairment
- synechia
- ulcerative colitis
Interactions
There are no drug interactions associated with Homatropine Hydrobromide products.
