Hexachlorophene Brand Name– Phisohex

What is Hexachlorophene

Hexachlorophene is a topical bacteriostatic agent. It is used as a surgical scrub and bacteriostatic skin cleanser.

Hexachlorophene also can be used to control outbreaks of gram-positive infections when other infection control measures have been unsuccessful. Infants are highly susceptible to hexachlorophene absorption; routine infant use is not recommended.

This drug was approved by the FDA in 1941.


  • skin antisepsis

For use as skin antisepsis

NOTE: Hexachlorophene may be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful

Side Effects

  1. abdominal pain
  2. anorexia
  3. contact dermatitis
  4. dehydration
  5. diarrhea
  6. erythema
  7. hypotension
  8. irritability
  9. myoclonia
  10. photosensitivity
  11. seizures
  12. skin irritation
  13. vomiting
  14. xerosis

Monitoring Parameters

  • laboratory monitoring not necessary


  • breast-feeding
  • burns
  • children
  • geriatric
  • ichthyosis
  • infants
  • neonates
  • occlusive dressing
  • ocular exposure
  • pregnancy
  • premature neonates
  • skin disease


There are no drug interactions associated with Hexachlorophene products.

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