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Hepatitis A Vaccine Inactivated Brand Names- Havrix | Vaqta
What is Hepatitis A Vaccine Inactivated
Hepatitis A vaccine is used to confer immunity against hepatitis A and is universally recommended for all children 12 to 23 months of age.
Hepatitis A vaccine is not effective in the prevention of other forms of hepatitis such as hepatitis B, hepatitis C, or hepatitis E.
There are currently 2 different products available; both require the administration of a series of at least 2 doses, although substantial protection is afforded by the initial (i.e., primary) dose.
Both products utilize inactivated whole virus propagated in MRC5 human diploid cells and are administered IM. Havrix contains no human blood or plasma-derived components.
Indications
- hepatitis A prophylaxis
Side Effects
- abdominal pain
- anaphylactic shock
- anaphylactoid reactions
- angioedema
- anorexia
- arthralgia
- chills
- constipation
- diarrhea
- dizziness
- drowsiness
- dysgeusia
- dyspnea
- encephalopathy
- erythema
- erythema multiforme
- fatigue
- fever
- Guillain-Barre syndrome
- headache
- hypertonia
- hypoesthesia
- injection site reaction
- insomnia
- irritability
- lymphadenopathy
- malaise
- myalgia
- myelitis
- nausea
- ocular irritation
- ocular pruritus
- paresthesias
- peripheral neuropathy
- photophobia
- pruritus
- rash
- seizures
- serum sickness
- syncope
- thrombocytopenia
- urticaria
- vasculitis
- vertigo
- vomiting
- wheezing
Monitoring Parameters
- hepatitis A serology
Contraindications
- agammaglobulinemia
- anticoagulant therapy
- breast-feeding
- coagulopathy
- fever
- hemophilia
- hepatic disease
- human immunodeficiency virus (HIV) infection
- hypogammaglobulinemia
- immunosuppression
- infection
- intravenous administration
- latex hypersensitivity
- neomycin hypersensitivity
- neoplastic disease
- pregnancy
- radiation therapy
- severe combined immunodeficiency (SCID)
- subcutaneous administration
- thrombocytopenia
- vitamin K deficiency
Interactions
- Ocrelizumab
- Siponimod