Hepatitis A Vaccine Inactivated

Hepatitis A Vaccine Inactivated Brand Names- Havrix | Vaqta

What is Hepatitis A Vaccine Inactivated

Hepatitis A vaccine is used to confer immunity against hepatitis A and is universally recommended for all children 12 to 23 months of age.

Hepatitis A vaccine is not effective in the prevention of other forms of hepatitis such as hepatitis B, hepatitis C, or hepatitis E.

There are currently 2 different products available; both require the administration of a series of at least 2 doses, although substantial protection is afforded by the initial (i.e., primary) dose.

Both products utilize inactivated whole virus propagated in MRC5 human diploid cells and are administered IM. Havrix contains no human blood or plasma-derived components.

Indications

  • hepatitis A prophylaxis

Side Effects

  1. abdominal pain
  2. anaphylactic shock
  3. anaphylactoid reactions
  4. angioedema
  5. anorexia
  6. arthralgia
  7. chills
  8. constipation
  9. diarrhea
  10. dizziness
  11. drowsiness
  12. dysgeusia
  13. dyspnea
  14. encephalopathy
  15. erythema
  16. erythema multiforme
  17. fatigue
  18. fever
  19. Guillain-Barre syndrome
  20. headache
  21. hypertonia
  22. hypoesthesia
  23. injection site reaction
  24. insomnia
  25. irritability
  26. lymphadenopathy
  27. malaise
  28. myalgia
  29. myelitis
  30. nausea
  31. ocular irritation
  32. ocular pruritus
  33. paresthesias
  34. peripheral neuropathy
  35. photophobia
  36. pruritus
  37. rash
  38. seizures
  39. serum sickness
  40. syncope
  41. thrombocytopenia
  42. urticaria
  43. vasculitis
  44. vertigo
  45. vomiting
  46. wheezing

Monitoring Parameters

  • hepatitis A serology

Contraindications

  • agammaglobulinemia
  • anticoagulant therapy
  • breast-feeding
  • coagulopathy
  • fever
  • hemophilia
  • hepatic disease
  • human immunodeficiency virus (HIV) infection
  • hypogammaglobulinemia
  • immunosuppression
  • infection
  • intravenous administration
  • latex hypersensitivity
  • neomycin hypersensitivity
  • neoplastic disease
  • pregnancy
  • radiation therapy
  • severe combined immunodeficiency (SCID)
  • subcutaneous administration
  • thrombocytopenia
  • vitamin K deficiency

Interactions

  • Ocrelizumab
  • Siponimod
You cannot copy content of this page