Glucocorticoid Properties of Corticosteroid Preparations

How do the Glucocorticoids properties of corticosteroids compare with cortisol?

The GC potency of medications correlates in part with the duration of biologic activity

Glucocorticoid Properties of Corticosteroid Preparations

GlucocorticoidGlucocorticoid Potency a
Short-acting
Hydrocortisone (cortisol)1
Cortisone0.8
Intermediate-acting
Prednisone4
Prednisolone4
Methylprednisolone5
Triamcinolone5
Long-acting
Paramethasone10
Betamethasone25
Dexamethasone30 to 40

a Potency is determined with cortisol as a reference value of 1.

Pearl: cortisol (Solu-Cortef) 20 mg = prednisone 5 mg = prednisolone 5 mg = Medrol 4 mg (Solu-Medrol) = Decadron 0.75 mg.

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