Efavirenz Emtricitabine Tenofovir Brand Name– Atripla
What is Efavirenz Emtricitabine Tenofovir
Efavirenz emtricitabine tenofovir is used for the treatment of human immunodeficiency virus (HIV) infection.
Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI), emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), and tenofovir is an acyclic nucleotide analog (i.e., nucleotide reverse transcriptase inhibitor).
NNRTI-based regimens, such as this, are commonly prescribed as initial treatment as they typically have a lower pill burden and preserve protease inhibitors (PIs) for later use.
The combination product allows for once-daily dosing using a single tablet. Although emtricitabine and tenofovir both exhibit activity against the hepatitis B virus (HBV), only tenofovir is indicated for this use.
The FDA approved package labeling has a Black Box Warning stating that safe and effective use has not been established for patients with HIV and HBV coinfection and that severe, acute exacerbations of hepatitis B have been reported in patients who discontinue either emtricitabine or tenofovir.
If treatment for HIV infection is discontinued in a patient with HBV coinfection, the patient should be closely monitored for several months for signs and symptoms of worsening hepatitis infection.
Due to the similarities between emtricitabine and lamivudine, emtricitabine containing products are not likely to be effective in individuals who display antimicrobial resistance to lamivudine.
Indications
- hepatitis B virus
- human immunodeficiency virus (HIV)
- human immunodeficiency virus (HIV) infection
NOTE: HIV guidelines recommend consideration be given to avoiding use of efavirenz-containing regimens in patients with pre-existing psychiatric illnesses, HIV-associated dementia (HAD), prolongation of the QTc interval, or who are receiving methadone as narcotic replacement therapy.
NOTE: HIV guidelines recommend consideration be given to avoiding use of tenofovir disoproxil fumarate-containing regimens in patients with renal disease and osteoporosis
Side Effects
- abdominal pain
- agitation
- amnesia
- angioedema
- anorexia
- anxiety
- arthralgia
- asthenia
- ataxia
- back pain
- bone fractures
- bone pain
- breast enlargement
- bullous rash
- chest pain (unspecified)
- confusion
- constipation
- cough
- Cushingoid features
- depression
- diabetes insipidus
- diarrhea
- dizziness
- drowsiness
- dyspepsia
- dyspnea
- elevated hepatic enzymes
- emotional lability
- encephalopathy
- erythema
- erythema multiforme
- euphoria
- exfoliative dermatitis
- Fanconi syndrome
- fatigue
- fever
- flushing
- glycosuria
- gynecomastia
- hallucinations
- headache
- hematuria
- hepatic decompensation
- hepatic failure
- hepatitis B exacerbation
- hepatomegaly
- hyperamylasemia
- hyperbilirubinemia
- hypercholesterolemia
- hyperglycemia
- hypertriglyceridemia
- hypoesthesia
- hypoglycemia
- hypokalemia
- hypophosphatemia
- impaired cognition
- infection
- insomnia
- interstitial nephritis
- lactic acidosis
- lipodystrophy
- maculopapular rash
- mania
- myalgia
- myasthenia
- myopathy
- nausea
- neuritis
- neutropenia
- nightmares
- osteomalacia
- osteopenia
- osteoporosis
- palpitations
- pancreatitis
- paranoia
- paresthesias
- peripheral neuropathy
- pharyngitis
- photosensitivity
- polyuria
- proteinuria
- pruritus
- psychosis
- QT prolongation
- rash
- renal failure (unspecified)
- renal tubular necrosis
- rhabdomyolysis
- rhinitis
- seizures
- sinusitis
- skin discoloration
- skin hyperpigmentation
- skin necrosis
- skin ulcer
- steatosis
- Stevens-Johnson syndrome
- suicidal ideation
- teratogenesis
- tinnitus
- toxic epidermal necrolysis
- tremor
- urticaria
- vertigo
- vesicular rash
- visual impairment
- vomiting
- weakness
Monitoring Parameters
- blood glucose
- CBC with differential
- CD4+ T cell count
- hepatitis B serology
- LFTs
- plasma hepatitis C RNA
- plasma HIV RNA
- pregnancy testing
- serum bilirubin (total and direct)
- serum cholesterol
- serum creatinine/BUN
- serum lipid profile
- serum phosphate
- serum triglycerides
- urinalysis
Contraindications
- alcoholism
- Asian patients
- autoimmune disease
- bipolar disorder
- Black patients
- bone fractures
- bradycardia
- breast-feeding
- cardiac arrhythmias
- cardiac disease
- children
- contraception requirements
- coronary artery disease
- depression
- diabetes mellitus
- driving or operating machinery
- exfoliative dermatitis
- females
- geriatric
- Graves’ disease
- Guillain-Barre syndrome
- heart failure
- hepatic disease
- hepatitis
- hepatitis B and HIV coinfection
- hepatitis B exacerbation
- hepatitis C and HIV coinfection
- hepatotoxicity or lactic acidosis
- Hispanic patients
- human immunodeficiency virus (HIV) infection resistance
- hypercholesterolemia
- hypertension
- hypertriglyceridemia
- hypocalcemia
- hypokalemia
- hypomagnesemia
- hypophosphatemia
- immune reconstitution syndrome
- infants
- lactic acidosis
- long QT syndrome
- malnutrition
- mania
- myocardial infarction
- neonates
- neurotoxicity
- obesity
- osteomalacia
- osteoporosis
- pregnancy
- pregnancy testing
- psychosis
- QT prolongation
- renal disease
- renal failure
- renal impairment
- reproductive risk
- schizophrenia
- seizure disorder
- seizures
- serious rash
- substance abuse
- suicidal ideation
- thyroid disease
Interactions
- Abacavir; Dolutegravir; Lamivudine
- Abacavir; Lamivudine, 3TC
- Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
- Abemaciclib
- Acalabrutinib
- Acetaminophen
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Pseudoephedrine
- Acetaminophen; Tramadol
- Aclidinium; Formoterol
- Acyclovir
- Adefovir
- Albuterol
- Albuterol; Ipratropium
- Alfentanil
- Alfuzosin
- Aliskiren; Amlodipine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Alogliptin; Metformin
- Alprazolam
- Amikacin
- Aminoglycosides
- Aminosalicylate sodium, Aminosalicylic acid
- Amiodarone
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amlodipine
- Amlodipine; Atorvastatin
- Amlodipine; Benazepril
- Amlodipine; Celecoxib
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amphotericin B
- Amphotericin B cholesteryl sulfate complex (ABCD)
- Amphotericin B lipid complex (ABLC)
- Amphotericin B liposomal (LAmB)
- Amprenavir
- Anagrelide
- Apalutamide
- Apomorphine
- Aprepitant, Fosaprepitant
- Arformoterol
- Aripiprazole
- Arsenic Trioxide
- Artemether; Lumefantrine
- Asenapine
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atazanavir
- Atazanavir; Cobicistat
- Atomoxetine
- Atorvastatin
- Atorvastatin; Ezetimibe
- Atovaquone
- Atovaquone; Proguanil
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Avanafil
- Avapritinib
- Axitinib
- Azithromycin
- Bacitracin
- Barbiturates
- Bedaquiline
- Benzhydrocodone; Acetaminophen
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Bepridil
- Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Boceprevir
- Bortezomib
- Bosentan
- Brentuximab vedotin
- Brexpiprazole
- Brigatinib
- Bromocriptine
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Budesonide; Formoterol
- Bupivacaine; Lidocaine
- Buprenorphine
- Buprenorphine; Naloxone
- Bupropion
- Bupropion; Naltrexone
- Buspirone
- Cabozantinib
- Canagliflozin; Metformin
- Cannabidiol
- Capmatinib
- Carbamazepine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carboplatin
- Cariprazine
- Carisoprodol
- Carvedilol
- Caspofungin
- Celecoxib
- Ceritinib
- Cevimeline
- Chlordiazepoxide
- Chlordiazepoxide; Clidinium
- Chloroquine
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpromazine
- Choline Salicylate; Magnesium Salicylate
- Cidofovir
- Cilostazol
- Ciprofloxacin
- Cisapride
- Cisplatin
- Citalopram
- Clarithromycin
- Clofarabine
- Clofazimine
- Clomipramine
- Clonazepam
- Clorazepate
- Clozapine
- Cobicistat
- Cobimetinib
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Colchicine
- Colchicine; Probenecid
- Colistimethate, Colistin, Polymyxin E
- Conivaptan
- Conjugated Estrogens
- Conjugated Estrogens; Bazedoxifene
- Conjugated Estrogens; Medroxyprogesterone
- Crizotinib
- Cyclophosphamide
- Cyclosporine
- Daclatasvir
- Dapagliflozin; Metformin
- Dapsone
- Darifenacin
- Darolutamide
- Darunavir
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Dasatinib
- Deflazacort
- Degarelix
- Delavirdine
- Desflurane
- Desipramine
- Deutetrabenazine
- Dextromethorphan; Promethazine
- Dextromethorphan; Quinidine
- Diazepam
- Dichlorphenamide
- Diclofenac
- Diclofenac; Misoprostol
- Didanosine, ddI
- Dienogest; Estradiol valerate
- Diflunisal
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Diltiazem
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Disopyramide
- Disulfiram
- Docetaxel
- Dofetilide
- Dolasetron
- Dolutegravir
- Dolutegravir; Lamivudine
- Dolutegravir; Rilpivirine
- Donepezil
- Donepezil; Memantine
- Doravirine
- Doravirine; Lamivudine; Tenofovir disoproxil fumarate
- Doxepin
- Doxercalciferol
- Doxorubicin
- Dronabinol
- Dronedarone
- Droperidol
- Drospirenone
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Echinacea
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elagolix; Estradiol; Norethindrone acetate
- Elbasvir; Grazoprevir
- Eletriptan
- Elexacaftor; tezacaftor; ivacaftor
- Eliglustat
- Elvitegravir
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Empagliflozin; Linagliptin
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Enalapril; Felodipine
- Encorafenib
- Enflurane
- Entrectinib
- Enzalutamide
- Eplerenone
- Erdafitinib
- Eribulin
- Erlotinib
- Ertugliflozin; Metformin
- Erythromycin
- Erythromycin; Sulfisoxazole
- Escitalopram
- Esomeprazole
- Esomeprazole; Naproxen
- Estazolam
- Estradiol
- Estradiol; Levonorgestrel
- Estradiol; Norethindrone
- Estradiol; Norgestimate
- Ethanol
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Ethosuximide
- Etodolac
- Etravirine
- Everolimus
- Ezetimibe; Simvastatin
- Ezogabine
- Famotidine; Ibuprofen
- Fedratinib
- Felodipine
- Fenoprofen
- Fentanyl
- Fingolimod
- Flecainide
- Flibanserin
- Fluconazole
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluphenazine
- Flurazepam
- Flurbiprofen
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Fluvastatin
- Fluvoxamine
- food
- Formoterol
- Formoterol; Mometasone
- Fosamprenavir
- Foscarnet
- Fostamatinib
- Ganciclovir
- Gemifloxacin
- Gemtuzumab Ozogamicin
- Gentamicin
- Gilteritinib
- Glasdegib
- Glecaprevir; Pibrentasvir
- Glimepiride
- Glimepiride; Pioglitazone
- Glimepiride; Rosiglitazone
- Glipizide; Metformin
- Glyburide; Metformin
- Glycopyrrolate; Formoterol
- Goserelin
- Granisetron
- grapefruit juice
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guanfacine
- Halogenated Anesthetics
- Haloperidol
- Halothane
- Histrelin
- Homatropine; Hydrocodone
- Hydantoins
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydroxychloroquine
- Hydroxyprogesterone
- Hydroxyzine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibrutinib
- Ibuprofen
- Ibuprofen; Oxycodone
- Ibuprofen; Pseudoephedrine
- Ibutilide
- Idelalisib
- Ifosfamide
- Iloperidone
- Imatinib
- Imipramine
- Indacaterol
- Indacaterol; Glycopyrrolate
- Indinavir
- Indomethacin
- Inotuzumab Ozogamicin
- Interferon Alfa-2a
- Interferon Alfa-2b
- Interferon Alfa-2b; Ribavirin
- Interferon Alfa-n3
- Interferon Alfacon-1
- Interferon Beta-1a
- Interferon Beta-1b
- Interferon Gamma-1b
- Interferons
- Iohexol
- Iopamidol
- Iopromide
- Ioversol
- Isavuconazonium
- Isoflurane
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Isosulfan Blue
- Isradipine
- Istradefylline
- Itraconazole
- Ivabradine
- Ivacaftor
- Ivosidenib
- Ixabepilone
- Kanamycin
- Ketoconazole
- Ketoprofen
- Ketorolac
- Lamivudine, 3TC
- Lamivudine, 3TC; Zidovudine, ZDV
- Lamivudine; Tenofovir Disoproxil Fumarate
- Lansoprazole; Naproxen
- Lapatinib
- Ledipasvir; Sofosbuvir
- Lefamulin
- Lemborexant
- Lenvatinib
- Lesinurad
- Lesinurad; Allopurinol
- Letermovir
- Leuprolide
- Leuprolide; Norethindrone
- Levalbuterol
- Levobupivacaine
- Levofloxacin
- Levomethadyl
- Levonorgestrel
- Lidocaine
- Lidocaine; Prilocaine
- Linagliptin
- Linagliptin; Metformin
- Lithium
- Lofexidine
- Long-acting beta-agonists
- Loperamide
- Loperamide; Simethicone
- Lopinavir; Ritonavir
- Lorlatinib
- Losartan
- Lovastatin
- Lovastatin; Niacin
- Lumacaftor; Ivacaftor
- Lumacaftor; Ivacaftor
- Lumateperone
- Lurasidone
- Lurbinectedin
- Macimorelin
- Magnesium Salicylate
- Maprotiline
- Maraviroc
- Meclofenamate Sodium
- Mefenamic Acid
- Mefloquine
- Meloxicam
- Meperidine; Promethazine
- Mestranol; Norethindrone
- Metaproterenol
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methadone
- Metronidazole
- Midostaurin
- Mifepristone
- Mirtazapine
- Mitotane
- Moxifloxacin
- Nabumetone
- Nanoparticle Albumin-Bound Paclitaxel
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Nefazodone
- Nelfinavir
- Neratinib
- Nevirapine
- Niacin; Simvastatin
- Nicardipine
- Nifedipine
- Nilotinib
- Nimodipine
- Nisoldipine
- Non-Ionic Contrast Media
- Non-oral combination contraceptives
- Nonsteroidal antiinflammatory drugs
- Norethindrone
- Norgestrel
- Nortriptyline
- Octreotide
- Ofloxacin
- Olanzapine
- Olaparib
- Olodaterol
- Ombitasvir; Paritaprevir; Ritonavir
- Omeprazole
- Omeprazole; Amoxicillin; Rifabutin
- Omeprazole; Sodium Bicarbonate
- Ondansetron
- Oral Contraceptives
- Oritavancin
- Orlistat
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Oxaprozin
- Oxybutynin
- Oxycodone
- Ozanimod
- Paclitaxel
- Palbociclib
- Pamidronate
- Panobinostat
- Paricalcitol
- Paromomycin
- Pasireotide
- Pazopanib
- Peginterferon Alfa-2a
- Peginterferon Alfa-2b
- Peginterferon beta-1a
- Pemigatinib
- Pentamidine
- Perampanel
- Perindopril; Amlodipine
- Perphenazine
- Perphenazine; Amitriptyline
- Pexidartinib
- Phenylephrine; Promethazine
- Pimavanserin
- Pimozide
- Pirbuterol
- Piroxicam
- Pitolisant
- Plazomicin
- Polymyxin B
- Polymyxins
- Posaconazole
- Praziquantel
- Primaquine
- Probenecid
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quazepam
- Quetiapine
- Quinidine
- Quinine
- Ranolazine
- Red Yeast Rice
- Regorafenib
- Repaglinide
- Ribavirin
- Ribociclib
- Ribociclib; Letrozole
- Rifabutin
- Rifampin
- Rifapentine
- Rifaximin
- Rilpivirine
- Riluzole
- Rimegepant
- Risperidone
- Ritonavir
- Rivaroxaban
- Rofecoxib
- Roflumilast
- Rolapitant
- Romidepsin
- Rucaparib
- Ruxolitinib
- Salicylates
- Salmeterol
- Salsalate
- Sapropterin
- Saquinavir
- Segesterone Acetate; Ethinyl Estradiol
- Selpercatinib
- Selumetinib
- Sertraline
- Sevoflurane
- Short-acting beta-agonists
- Sibutramine
- Sildenafil
- Simeprevir
- Simvastatin
- Simvastatin; Sitagliptin
- Siponimod
- Sirolimus
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Solifenacin
- Somatropin, rh-GH
- Sonidegib
- Sorafenib
- Sotalol
- St. John’s Wort, Hypericum perforatum
- Streptomycin
- Sufentanil
- Sulindac
- Sunitinib
- Suvorexant
- Tacrolimus
- Tadalafil
- Tafamidis
- Tamoxifen
- Tasimelteon
- Tazemetostat
- Tedizolid
- Telaprevir
- Telavancin
- Telithromycin
- Telotristat Ethyl
- Temsirolimus
- Terbinafine
- Terbutaline
- Testosterone
- Tetrabenazine
- Tezacaftor; Ivacaftor
- Thioridazine
- Ticagrelor
- Tiotropium; Olodaterol
- Tipranavir
- Tobramycin
- Tolbutamide
- Tolmetin
- Tolterodine
- Tolvaptan
- Toremifene
- Tramadol
- Trandolapril; Verapamil
- Trazodone
- Triclabendazole
- Tricyclic antidepressants
- Trifluoperazine
- Trimetrexate
- Trimipramine
- Triptorelin
- Trospium
- Tucatinib
- Ubrogepant
- Ulipristal
- Umeclidinium; Vilanterol
- Valacyclovir
- Valdecoxib
- Valganciclovir
- Vancomycin
- Vandetanib
- Vardenafil
- Vemurafenib
- Venetoclax
- Venlafaxine
- Verapamil
- Vorapaxar
- Voriconazole
- Vorinostat
- Voxelotor
- Warfarin
- Zanubrutinib
- Ziprasidone
- Zoledronic Acid
- Zolpidem
- Zonisamide
