Dextromethorphan Guaifenesin Phenylephrine

Dextromethorphan Guaifenesin Phenylephrine Brand Names

Actidom DMX | Actinel DM | Ambi | Anextuss | Aquanaz | Aquatab C | Broncotron PED | Certuss D | Dacex PE | Dacex-DM | Deconex DMX | Dexcon PE | Dexcon-DM | DuraMAX | Duraphen DM | Duraphen Forte | Duraphen II DM | Duravent DM | Endacon | ExeCof | ExeTuss-DM | G Phen DM | GDP-EX | Giltuss | Giltuss Children’s Cough & Cold | Giltuss Cough & Cold | Giltuss Pediatric | Giltuss TR | Guaifen DM | Guaphen Forte | Guaphen II DM | Guiafen II DM | Maxiphen DM | Maxiphen-G DM | Mucinex Children’s Congestion & Cough | Mucinex Children’s Multi-Symptom Cold | Mucinex Fast-Max | Mucinex Fast-Max Severe Congestion & Cough | Mucinex Junior Cough & Congestion | Mucinex Multi-Symptom Cold Children’s | Nivanex DMX | Numonyl DX | Phlemex Forte | Phlemex-PE | Q-Tussin CF | Robafen CF | Robitussin Adult Peak Cold | Robitussin CF Adult Peak Multi-Symptom | Robitussin CF Children’s Cough & Cold | Sinutuss DM | TriTuss | TriTuss ER | Tussafed EX | Tussafed-EX | Tussidex | Tussi-Pres | Tusso-DM | Tusso-DMR | Tusso-XR | Vana Tab DM | VanaCof DM | VanaCof DMX | Z-Dex | Z-Dex Pediatric | Zotex | Zotex LAX | Zotex Pediatric | Zotex-EX | Zotex-LA | ZTuss DM

What is Dextromethorphan Guaifenesin Phenylephrine

Dextromethorphan guaifenesin phenylephrine are used together in oral preparations to treat cough and congestion due to colds, acute respiratory infections, acute and chronic bronchitis, and hay fever.

Dextromethorphan is a centrally acting non-opioid cough suppressant.

Guaifenesin loosens and thins phlegm and bronchial secretions to ease expectoration.

Although guaifenesin may be used as an expectorant in both productive and non-productive coughs, it is especially useful in the treatment of dry, non-productive coughs, which tend to injure the respiratory mucous membranes.

Phenylephrine is a sympathomimetic amine that is used as a decongestant.

Indications

1. common cold
2. cough
3. nasal congestion

For the temporary relief of nasal congestion and cough associated with acute respiratory tract infections, such as the common cold and related conditions (e.g., sinusitis, acute bronchitis)

Side Effects

1. anaphylactoid reactions
2. angina
3. anxiety
4. arrhythmia exacerbation
5. ataxia
6. blurred vision
7. bowel ischemia
8. colitis
9. confusion
10. contact dermatitis
11. diarrhea
12. dizziness
13. drowsiness
14. dysarthria
15. dystonic reaction
16. erythema
17. fatigue
18. hallucinations
19. headache
20. hypertension
21. insomnia
22. intracranial bleeding
23. irritability
24. nausea
25. nephrolithiasis
26. nystagmus
27. ocular hypertension
28. palpitations
29. rash
30. respiratory depression
31. restlessness
32. seizures
33. serotonin syndrome
34. sinus tachycardia
35. stroke
36. tremor
37. urticaria
38. ventricular tachycardia

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• angina
• asthma
• bladder obstruction
• breast-feeding
• bronchitis
• cardiac arrhythmias
• cardiac disease
• cardiomyopathy
• cerebrovascular disease
• children
• coronary artery disease
• diabetes mellitus
• driving or operating machinery
• emphysema
• geriatric
• hepatic disease
• hypertension
• hyperthyroidism
• infants
• labor
• MAOI therapy
• peripheral vascular disease
• pregnancy
• prostatic hypertrophy
• tobacco smoking
• urinary retention

Interactions

• Abiraterone
• Acarbose
• Acebutolol
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Codeine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Pseudoephedrine
• Aclidinium; Formoterol
• Acrivastine; Pseudoephedrine
• Albiglutide
• Albuterol
• Albuterol; Ipratropium
• Alfentanil
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Alogliptin; Metformin
• Alogliptin; Pioglitazone
• Alpha-blockers
• Alpha-glucosidase Inhibitors
• Alprazolam
• Ambrisentan
• Amiloride
• Amiloride; Hydrochlorothiazide, HCTZ
• Amiodarone
• Amitriptyline; Chlordiazepoxide
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amoxapine
• Angiotensin II receptor antagonists
• Angiotensin-converting enzyme inhibitors
• Arformoterol
• Artemether; Lumefantrine
• Articaine; Epinephrine
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol; Codeine
• Atazanavir; Cobicistat
• Atenolol
• Atenolol; Chlorthalidone
• Atomoxetine
• Atropine
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Edrophonium
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Avanafil
• Azelastine; Fluticasone
• Azilsartan; Chlorthalidone
• Beclomethasone
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendroflumethiazide; Nadolol
• Benzodiazepines
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Beta-blockers
• Betamethasone
• Betaxolol
• Bethanechol
• Bisoprolol
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Bosentan
• Bretylium
• Brimonidine; Timolol
• Bromocriptine
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Budesonide
• Budesonide; Formoterol
• Bumetanide
• Buprenorphine
• Buprenorphine; Naloxone
• Butorphanol
• Caffeine
• Caffeine; Ergotamine
• Calcium-channel blockers
• Canagliflozin
• Canagliflozin; Metformin
• Candesartan; Hydrochlorothiazide, HCTZ
• Captopril; Hydrochlorothiazide, HCTZ
• Carbetapentane; Pseudoephedrine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Pseudoephedrine
• Cardiac glycosides
• Carteolol
• Carvedilol
• Celecoxib
• Cetirizine; Pseudoephedrine
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chlordiazepoxide
• Chlordiazepoxide; Clidinium
• Chlorothiazide
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Pseudoephedrine
• Chlorthalidone
• Chlorthalidone; Clonidine
• Ciclesonide
• Cinacalcet
• Citalopram
• Clevidipine
• Clobazam
• Clonazepam
• Clonidine
• Clorazepate
• Cobicistat
• Cocaine
• Codeine
• Codeine; Guaifenesin
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• Colchicine
• Colchicine; Probenecid
• Corticosteroids
• Cortisone
• Dacomitinib
• Dapagliflozin
• Dapagliflozin; Metformin
• Dapagliflozin; Saxagliptin
• Darifenacin
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Deflazacort
• Delavirdine
• Desloratadine; Pseudoephedrine
• Desmopressin
• Desvenlafaxine
• Dexamethasone
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dexmethylphenidate
• Dextromethorphan; Guaifenesin; Pseudoephedrine
• Diazepam
• Diethylpropion
• Digitoxin
• Digoxin
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Dihydroergotamine
• Diltiazem
• Dipeptidyl Peptidase-4 Inhibitors
• Donepezil; Memantine
• Dorzolamide; Timolol
• Doxazosin
• Dronabinol
• Dronedarone
• Dulaglutide
• Duloxetine
• Dyphylline
• Dyphylline; Guaifenesin
• Eliglustat
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Empagliflozin
• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Empagliflozin; Metformin
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Enflurane
• Epinephrine
• Epoprostenol
• Eprosartan; Hydrochlorothiazide, HCTZ
• Ergoloid Mesylates
• Ergonovine
• Ergot alkaloids
• Ergotamine
• Ertugliflozin
• Ertugliflozin; Metformin
• Ertugliflozin; Sitagliptin
• Escitalopram
• Esmolol
• Estazolam
• Ethacrynic Acid
• Exenatide
• Fedratinib
• Felodipine
• Fentanyl
• Fexofenadine; Pseudoephedrine
• Fludrocortisone
• Flunisolide
• Fluoxetine
• Fluoxetine; Olanzapine
• Flurazepam
• Fluticasone
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvoxamine
• Formoterol
• Formoterol; Mometasone
• Fosinopril; Hydrochlorothiazide, HCTZ
• Furosemide
• Ginger, Zingiber officinale
• Givosiran
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glipizide; Metformin
• Glyburide; Metformin
• Glycopyrrolate; Formoterol
• grapefruit juice
• Green Tea
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guaifenesin; Pseudoephedrine
• Guanabenz
• Haloperidol
• Halothane
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydrocortisone
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibuprofen; Pseudoephedrine
• Iloprost
• Imatinib
• Incretin Mimetics
• Indacaterol
• Indacaterol; Glycopyrrolate
• Indapamide
• Insulin Degludec; Liraglutide
• Insulin Glargine; Lixisenatide
• Insulins
• Iobenguane I 131
• Ionic Contrast Media
• Isocarboxazid
• Isoflurane
• Isradipine
• Labetalol
• Lasmiditan
• Levalbuterol
• Levobetaxolol
• Levobunolol
• Levomilnacipran
• Levothyroxine
• Levothyroxine; Liothyronine (Porcine)
• Levothyroxine; Liothyronine (Synthetic)
• Linagliptin; Metformin
• Linezolid
• Liothyronine
• Liraglutide
• Lixisenatide
• Loop diuretics
• Loratadine; Pseudoephedrine
• Lorazepam
• Lorcaserin
• Loxapine
• Macitentan
• Maprotiline
• Mecamylamine
• Meglitinides
• Memantine
• Metaproterenol
• Metformin
• Metformin; Pioglitazone
• Metformin; Repaglinide
• Metformin; Rosiglitazone
• Metformin; Saxagliptin
• Metformin; Sitagliptin
• Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
• Methyclothiazide
• Methyldopa
• Methylene Blue
• Methylergonovine
• Methylphenidate
• Methylprednisolone
• Methysergide
• Metolazone
• Metoprolol
• Midazolam
• Midodrine
• Miglitol
• Milnacipran
• Mirabegron
• Mirtazapine
• Mometasone
• Monoamine oxidase inhibitors
• Nabilone
• Nadolol
• Nafarelin
• Naproxen; Pseudoephedrine
• Nebivolol
• Nebivolol; Valsartan
• Nefazodone
• Nicardipine
• Nicotine
• Nifedipine
• Nimodipine
• Nisoldipine
• Nitrates
• Non-Ionic Contrast Media
• Oritavancin
• Oxazepam
• Oxytocin
• Ozanimod
• Panobinostat
• Paroxetine
• Pazopanib
• Peginterferon Alfa-2b
• Penbutolol
• Pergolide
• Perindopril; Amlodipine
• Phendimetrazine
• Phenelzine
• Phenothiazines
• Phenoxybenzamine
• Phentermine
• Phentermine; Topiramate
• Phentolamine
• Phosphodiesterase inhibitors
• Pindolol
• Pioglitazone
• Pirbuterol
• Potassium-sparing diuretics
• Pramlintide
• Prazosin
• Prednisolone
• Prednisone
• Prilocaine; Epinephrine
• Procarbazine
• Propafenone
• Propofol
• Propranolol
• Pseudoephedrine
• Quazepam
• Quinine
• Racepinephrine
• Rasagiline
• Reserpine
• Riociguat
• Rolapitant
• Rosiglitazone
• Safinamide
• Salmeterol
• Selegiline
• Selexipag
• Semaglutide
• Serotonin-Receptor Agonists
• Sertraline
• Sevoflurane
• SGLT2 Inhibitors
• Sibutramine
• Sildenafil
• Solriamfetol
• Sotalol
• Spironolactone
• St. John’s Wort, Hypericum perforatum
• Sulfonylureas
• Tadalafil
• Tedizolid
• Temazepam
• Terazosin
• Terbinafine
• Terbutaline
• Theophylline, Aminophylline
• Thiazide diuretics
• Thiazolidinediones
• Thiothixene
• Thyroid hormones
• Timolol
• Tocilizumab
• Torsemide
• Trandolapril; Verapamil
• Tranylcypromine
• Treprostinil
• Triamcinolone
• Triamterene
• Triazolam
• Tricyclic antidepressants
• Umeclidinium; Vilanterol
• Vardenafil
• Vasodilators
• Vemurafenib
• Venlafaxine
• Verapamil
• Vilazodone
• Vortioxetine
• Yohimbine