Betrixaban

Betrixaban Brand Name– BEVYXXA

What is Betrixaban

Betrixaban is an oral factor Xa inhibitor indicated for venous thromboembolism (VTE) prophylaxis in adults hospitalized for an acute medical illness who are at risk for VTE due to moderate or severe restricted mobility or other risk factors.

Unlike some other anticoagulants, the anticoagulant effect of betrixaban cannot be monitored with standard laboratory testing and is not easily reversed.

Indications

  • deep venous thrombosis (DVT) prophylaxis
  • pulmonary embolism prophylaxis

For venous thromboembolism prophylaxis (i.e., deep venous thrombosis (DVT) prophylaxis, pulmonary embolism prophylaxis) in at-risk, acutely ill, hospitalized medical patients

Side Effects

  1. bleeding
  2. constipation
  3. diarrhea
  4. epistaxis
  5. GI bleeding
  6. headache
  7. hematuria
  8. hypertension
  9. hypokalemia
  10. infection
  11. intracranial bleeding
  12. nausea
  13. ocular hemorrhage
  14. QT prolongation
  15. spinal hematoma

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • bleeding
  • breast-feeding
  • coagulopathy
  • epidural anesthesia
  • hepatic disease
  • lumbar puncture
  • obstetric delivery
  • pregnancy
  • prosthetic heart valves
  • renal disease
  • renal failure
  • renal impairment
  • spinal anesthesia

Interactions

  • Abciximab
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Ado-Trastuzumab emtansine
  • Alteplase
  • Altretamine
  • Amiodarone
  • Amlodipine; Celecoxib
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Anagrelide
  • Antithrombin III
  • Antithymocyte Globulin
  • Apalutamide
  • Apixaban
  • Argatroban
  • Arsenic Trioxide
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Atazanavir; Cobicistat
  • Atomoxetine
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Bivalirudin
  • Brigatinib
  • Cabozantinib
  • Caplacizumab
  • Carbamazepine
  • Carbenicillin
  • Carvedilol
  • Celecoxib
  • Chlorambucil
  • Chloroquine
  • Cilostazol
  • Citalopram
  • Clarithromycin
  • Clofarabine
  • Clopidogrel
  • Cobicistat
  • Collagenase
  • Conivaptan
  • Cyclosporine
  • Cytarabine, ARA-C
  • Dabigatran
  • Daclatasvir
  • Dalteparin
  • Darunavir; Cobicistat
  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
  • Dasatinib
  • Decitabine
  • Defibrotide
  • Denileukin Diftitox
  • Desirudin
  • Dextran
  • Dextromethorphan; Quinidine
  • Diclofenac
  • Diclofenac; Misoprostol
  • Diflunisal
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Dipyridamole
  • Dronedarone
  • Drotrecogin Alfa
  • Edoxaban
  • Elagolix
  • Elexacaftor; tezacaftor; ivacaftor
  • Eliglustat
  • Eltrombopag
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Enoxaparin
  • Epoprostenol
  • Eptifibatide
  • Erythromycin
  • Erythromycin; Sulfisoxazole
  • Escitalopram
  • Esomeprazole; Naproxen
  • Esterified Estrogens; Methyltestosterone
  • Estramustine
  • Etodolac
  • Etravirine
  • Factor X
  • Famotidine; Ibuprofen
  • Fenoprofen
  • Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
  • Flibanserin
  • Floxuridine
  • Fluorouracil, 5-FU
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Flurbiprofen
  • Fluvoxamine
  • Folate analogs
  • Fondaparinux
  • Fosamprenavir
  • Fosphenytoin
  • Fostamatinib
  • Garlic, Allium sativum
  • Ginger, Zingiber officinale
  • Ginkgo, Ginkgo biloba
  • Glecaprevir; Pibrentasvir
  • Green Tea
  • Hemin
  • Heparin
  • Hydrocodone; Ibuprofen
  • Hydroxychloroquine
  • Hydroxyurea
  • Ibritumomab Tiuxetan
  • Ibrutinib
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Icosapent ethyl
  • Iloprost
  • Indomethacin
  • Inotersen
  • Interferon Alfa-2a
  • Interferon Alfa-2b
  • Interferon Alfa-2b; Ribavirin
  • Interferon Alfa-n3
  • Interferon Alfacon-1
  • Intravenous Lipid Emulsions
  • Isavuconazonium
  • Isoniazid, INH; Pyrazinamide, PZA; Rifampin
  • Isoniazid, INH; Rifampin
  • Istradefylline
  • Itraconazole
  • Ivacaftor
  • Ketoconazole
  • Ketoprofen
  • Ketorolac
  • Lansoprazole; Naproxen
  • Lapatinib
  • Ledipasvir; Sofosbuvir
  • Lepirudin
  • Lomitapide
  • Lomustine, CCNU
  • Lopinavir; Ritonavir
  • Lumacaftor; Ivacaftor
  • Lumacaftor; Ivacaftor
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Mefloquine
  • Meloxicam
  • Methoxsalen
  • Methylsulfonylmethane, MSM
  • Methyltestosterone
  • Mifepristone
  • Miltefosine
  • Mycophenolate
  • Nabumetone
  • Nandrolone Decanoate
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Natural Antineoplastics
  • Nelarabine
  • Nelfinavir
  • Neratinib
  • Nintedanib
  • Nonsteroidal antiinflammatory drugs
  • Obinutuzumab
  • Omacetaxine
  • Ombitasvir; Paritaprevir; Ritonavir
  • Osimertinib
  • Oxandrolone
  • Oxaprozin
  • Paroxetine
  • Pentosan
  • Phenobarbital
  • Phenytoin
  • Piperacillin
  • Piperacillin; Tazobactam
  • Piroxicam
  • Ponatinib
  • Posaconazole
  • Prasterone, Dehydroepiandrosterone, DHEA (Dietary Supplements)
  • Prasterone, Dehydroepiandrosterone, DHEA (FDA-approved)
  • Prasugrel
  • Primidone
  • Propafenone
  • Prothrombin Complex Concentrate, Human
  • Quinidine
  • Quinine
  • Ranolazine
  • Reteplase, r-PA
  • Rifampin
  • Ritonavir
  • Rivaroxaban
  • Rofecoxib
  • Rolapitant
  • Sapropterin
  • Saquinavir
  • Sarecycline
  • Selective norepinephrine reuptake inhibitors
  • Selective serotonin reuptake inhibitors
  • Serotonin norepinephrine reuptake inhibitors
  • Sertraline
  • Simeprevir
  • Sodium Iodide
  • Sofosbuvir; Velpatasvir
  • Sofosbuvir; Velpatasvir; Voxilaprevir
  • Sorafenib
  • St. John’s Wort, Hypericum perforatum
  • Streptokinase
  • Sulfinpyrazone
  • Sulindac
  • Telaprevir
  • Telithromycin
  • Temsirolimus
  • Tenecteplase
  • Tezacaftor; Ivacaftor
  • Thrombin Inhibitors
  • Thrombolytic Agents
  • Ticagrelor
  • Ticarcillin
  • Ticarcillin; Clavulanic Acid
  • Ticlopidine
  • Tipranavir
  • Tirofiban
  • Tolmetin
  • Trandolapril; Verapamil
  • Trazodone
  • Treprostinil
  • Tretinoin, ATRA
  • Urokinase
  • Valdecoxib
  • Vemurafenib
  • Venetoclax
  • Verapamil
  • Verteporfin
  • Vilazodone
  • Vorapaxar
  • Vortioxetine
  • Warfarin
  • Zonisamide
15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856