What's on this Page
Amiodarone Brand Names
Cordarone | Nexterone | Pacerone
What is Amiodarone
Amiodarone is a class III antiarrhythmic agent used for the treatment of tachyarrhythmias.
Although amiodarone is FDA-approved only for the treatment of ventricular arrhythmias, it is widely used for supraventricular arrhythmias, especially for the pharmacological cardioversion of atrial fibrillation and maintenance of normal sinus rhythm.
Amiodarone and sotalol are equally efficacious in converting atrial fibrillation to sinus rhythm; however, amiodarone is superior to sotalol for maintaining sinus rhythm.
Amiodarone is also more effective than propafenone and other class I agents for the maintenance of sinus rhythm.
Amiodarone may be considered during cardiac arrest when ventricular fibrillation or pulseless ventricular tachycardia is unresponsive to cardiopulmonary resuscitation (CPR), defibrillation, and vasopressor therapy.
Amiodarone may also be considered for stable wide-complex tachycardia or polymorphic ventricular tachycardia.
Guidelines suggest amiodarone as an alternative treatment for the prevention of atrial fibrillation after cardiac surgery in patients for whom first-line therapy (e.g., beta-blockers) is contraindicated.
Atrial tachyarrhythmias occurred significantly less often in patients receiving oral amiodarone compared to those receiving placebo (16.1% vs. 29.5%, respectively) after nonemergent coronary artery bypass graft (CABG) surgery and/or valve replacement or repair in the PAPABEAR trial.
Although amiodarone is associated with several potentially significant and sometimes fatal adverse effects, it has not been associated with proarrhythmias as frequently as other antiarrhythmics.
Indications
- atrial fibrillation
- atrial fibrillation prophylaxis
- atrial flutter
- cardiac surgery
- cardiopulmonary resuscitation
- heart failure
- ventricular fibrillation
- ventricular tachycardia
For the treatment of life-threatening recurrent ventricular fibrillation or hemodynamically unstable (symptomatic) sustained ventricular tachycardia, including post-myocardial infarction (MI) patients
Side Effects
- abdominal pain
- acute respiratory distress syndrome (ARDS)
- agranulocytosis
- akinesia
- alopecia
- anaphylactic shock
- anaphylactoid reactions
- angioedema
- anorexia
- aplastic anemia
- arrhythmia exacerbation
- arthralgia
- ataxia
- atrial fibrillation
- AV block
- bleeding
- blurred vision
- bradycardia
- bronchiolitis obliterans
- bronchospasm
- cardiac arrest
- cholestasis
- cirrhosis
- confusion
- constipation
- corneal deposits
- cough
- cyanosis
- delirium
- diarrhea
- dizziness
- Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
- dyspnea
- ecchymosis
- edema
- elevated hepatic enzymes
- eosinophilia
- eosinophilic pneumonia
- epididymitis
- erythema
- erythema multiforme
- exfoliative dermatitis
- fatigue
- fever
- flushing
- goiter
- hallucinations
- headache
- heart failure
- hemolytic anemia
- hemoptysis
- hepatic failure
- hepatitis
- hepatotoxicity
- hyperhidrosis
- hyperthyroidism
- hypoesthesia
- hypotension
- hypothyroidism
- hypoxia
- impotence (erectile dysfunction)
- injection site reaction
- insomnia
- involuntary movements
- libido decrease
- lupus-like symptoms
- malaise
- myopathy
- nausea
- neutropenia
- optic neuritis
- pancreatitis
- pancytopenia
- paresthesias
- periarteritis
- peripheral neuropathy
- phlebitis
- photosensitivity
- pleural effusion
- pneumonitis
- pruritus
- pseudotumor cerebri
- pulmonary edema
- pulmonary fibrosis
- pulmonary toxicity
- QT prolongation
- rash
- renal failure (unspecified)
- respiratory arrest
- rhabdomyolysis
- SIADH
- skin discoloration
- skin necrosis
- Stevens-Johnson syndrome
- thrombocytopenia
- thrombosis
- thrombotic thrombocytopenic purpura (TTP)
- thyrotoxicosis
- torsade de pointes
- toxic epidermal necrolysis
- tremor
- urticaria
- vasculitis
- ventricular fibrillation
- ventricular tachycardia
- visual impairment
- vomiting
- weakness
- wheezing
- xerostomia
Monitoring Parameters
- CBC
- chest x-ray
- ECG
- LFTs
- ophthalmologic exam
- pulmonary function tests (PFTs)
- thyroid function tests (TFTs)
Contraindications
- amiodarone-induced liver toxicity
- Amiodarone-induced lung toxicity
- apheresis
- arrhythmia exacerbation
- AV block
- bradycardia
- breast-feeding
- cardiogenic shock
- cardiomyopathy
- celiac disease
- children
- chronic obstructive pulmonary disease (COPD)
- diarrhea
- electrolyte imbalance
- females
- fever
- geriatric
- goiter
- halothane anesthesia
- heart failure
- hepatic disease
- hepatitis
- hepatotoxicity
- human immunodeficiency virus (HIV) infection
- hyperparathyroidism
- hyperthyroidism
- hypocalcemia
- hypokalemia
- hypomagnesemia
- hypotension
- hypothermia
- hypothyroidism
- hypovolemia
- infants
- infertility
- iodine hypersensitivity
- long QT syndrome
- myocardial infarction
- neonates
- neurological disease
- ocular surgery
- optic neuritis
- peripheral neuropathy
- pheochromocytoma
- pneumonitis
- pregnancy
- pulmonary disease
- pulmonary fibrosis
- QT prolongation
- requires an experienced clinician
- respiratory distress syndrome
- respiratory insufficiency
- rheumatoid arthritis
- sick sinus syndrome
- sickle cell disease
- sleep deprivation
- stroke
- sunlight (UV) exposure
- surgery
- systemic lupus erythematosus (SLE)
- thyroid disease
- thyrotoxicosis
- ventricular dysfunction
- visual disturbance
Interactions
- Abarelix
- Abemaciclib
- Acalabrutinib
- Acebutolol
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Propoxyphene
- Acetaminophen; Tramadol
- Aclidinium; Formoterol
- Afatinib
- Albuterol
- Albuterol; Ipratropium
- Alfentanil
- Alfuzosin
- Aliskiren; Amlodipine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Alprazolam
- Amiloride; Hydrochlorothiazide, HCTZ
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amlodipine
- Amlodipine; Atorvastatin
- Amlodipine; Benazepril
- Amlodipine; Celecoxib
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amphotericin B
- Amphotericin B cholesteryl sulfate complex (ABCD)
- Amphotericin B lipid complex (ABLC)
- Amphotericin B liposomal (LAmB)
- Amprenavir
- Anagrelide
- Apalutamide
- Apixaban
- Apomorphine
- Aprepitant, Fosaprepitant
- Arformoterol
- Aripiprazole
- Arsenic Trioxide
- Artemether; Lumefantrine
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Oxycodone
- Atazanavir
- Atazanavir; Cobicistat
- Atenolol
- Atenolol; Chlorthalidone
- Atomoxetine
- Atorvastatin
- Atorvastatin; Ezetimibe
- Avanafil
- Avapritinib
- Avatrombopag
- Azilsartan; Chlorthalidone
- Azithromycin
- Bedaquiline
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Benazepril; Hydrochlorothiazide, HCTZ
- Bendroflumethiazide; Nadolol
- Benzhydrocodone; Acetaminophen
- Betaxolol
- Betrixaban
- Bicalutamide
- Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Boceprevir
- Bortezomib
- Bosentan
- Brexpiprazole
- Brigatinib
- Brimonidine; Timolol
- Bromocriptine
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Guaifenesin
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Budesonide
- Budesonide; Formoterol
- Bumetanide
- Bupivacaine; Lidocaine
- Buprenorphine
- Buprenorphine; Naloxone
- Buspirone
- Caffeine
- Caffeine; Ergotamine
- Candesartan; Hydrochlorothiazide, HCTZ
- Cannabidiol
- Captopril; Hydrochlorothiazide, HCTZ
- Carbamazepine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Phenylephrine
- Cariprazine
- Carteolol
- Carvedilol
- Celecoxib
- Cenobamate
- Ceritinib
- Cerivastatin
- Cevimeline
- Chlophedianol; Guaifenesin; Phenylephrine
- Chlordiazepoxide
- Chlordiazepoxide; Clidinium
- Chloroquine
- Chlorothiazide
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dextromethorphan
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Phenylephrine
- Chlorpromazine
- Chlorthalidone
- Chlorthalidone; Clonidine
- Cholestyramine
- Cilostazol
- Cimetidine
- Cinacalcet
- Ciprofloxacin
- Cisapride
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clonazepam
- Clonidine
- Clorazepate
- Clozapine
- Cobicistat
- Cobimetinib
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Colchicine
- Colchicine; Probenecid
- Conivaptan
- Conjugated Estrogens
- Conjugated Estrogens; Bazedoxifene
- Conjugated Estrogens; Medroxyprogesterone
- Crizotinib
- Cyclophosphamide
- Cyclosporine
- Dabigatran
- Daclatasvir
- Danazol
- Dapagliflozin; Saxagliptin
- Darifenacin
- Darunavir
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Dasatinib
- Deferasirox
- Deflazacort
- Degarelix
- Delavirdine
- Desflurane
- Desipramine
- Deutetrabenazine
- Dexamethasone
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dextromethorphan
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin
- Dextromethorphan; Guaifenesin; Phenylephrine
- Dextromethorphan; Guaifenesin; Potassium Guaiacolsulfonate
- Dextromethorphan; Guaifenesin; Pseudoephedrine
- Dextromethorphan; Promethazine
- Dextromethorphan; Quinidine
- Diazepam
- Diclofenac
- Diclofenac; Misoprostol
- Dienogest; Estradiol valerate
- Diethylstilbestrol, DES
- Digoxin
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Dihydroergotamine
- Diltiazem
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Diphenhydramine; Phenylephrine
- Disopyramide
- Dofetilide
- Dolasetron
- Dolutegravir; Rilpivirine
- Donepezil
- Donepezil; Memantine
- Doravirine; Lamivudine; Tenofovir disoproxil fumarate
- Dorzolamide; Timolol
- Doxepin
- Doxercalciferol
- Doxorubicin
- Dronabinol
- Dronedarone
- Droperidol
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Duloxetine
- Dutasteride
- Dutasteride; Tamsulosin
- Duvelisib
- Edoxaban
- Efavirenz
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elagolix
- Elagolix; Estradiol; Norethindrone acetate
- Elbasvir; Grazoprevir
- Eletriptan
- Elexacaftor; tezacaftor; ivacaftor
- Eliglustat
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Emtricitabine; Tenofovir disoproxil fumarate
- Enalapril; Felodipine
- Enalapril; Hydrochlorothiazide, HCTZ
- Encainide
- Encorafenib
- Enflurane
- Entrectinib
- Enzalutamide
- Eplerenone
- Eprosartan; Hydrochlorothiazide, HCTZ
- Erdafitinib
- Ergonovine
- Ergotamine
- Eribulin
- Erlotinib
- Erythromycin
- Erythromycin; Sulfisoxazole
- Escitalopram
- Eslicarbazepine
- Esmolol
- Esomeprazole; Naproxen
- Estazolam
- Esterified Estrogens
- Esterified Estrogens; Methyltestosterone
- Estradiol
- Estradiol Cypionate; Medroxyprogesterone
- Estradiol; Levonorgestrel
- Estradiol; Norethindrone
- Estradiol; Norgestimate
- Estradiol; Progesterone
- Estrogens
- Estropipate
- Eszopiclone
- Ethacrynic Acid
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Etomidate
- Etravirine
- Everolimus
- Ezetimibe; Simvastatin
- Ezogabine
- Famotidine; Ibuprofen
- Fedratinib
- Felodipine
- Fentanyl
- Fesoterodine
- Fingolimod
- Flecainide
- Flibanserin
- Fluconazole
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluphenazine
- Flurazepam
- Flurbiprofen
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Fluvastatin
- Fluvoxamine
- food
- Formoterol
- Formoterol; Mometasone
- Fosamprenavir
- Foscarnet
- Fosinopril; Hydrochlorothiazide, HCTZ
- Fospropofol
- Furosemide
- Gemifloxacin
- Gemtuzumab Ozogamicin
- Gilteritinib
- Glasdegib
- Glecaprevir; Pibrentasvir
- Glycopyrrolate; Formoterol
- Goserelin
- Granisetron
- grapefruit juice
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Phenylephrine
- Guanfacine
- Halogenated Anesthetics
- Haloperidol
- Halothane
- Histrelin
- Homatropine; Hydrocodone
- Hydantoins
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydroxychloroquine
- Hydroxyzine
- Ibrutinib
- Ibuprofen
- Ibuprofen; Oxycodone
- Ibuprofen; Pseudoephedrine
- Ibutilide
- Idelalisib
- Ifosfamide
- Iloperidone
- Imatinib
- Imipramine
- Indacaterol
- Indacaterol; Glycopyrrolate
- Indapamide
- Indinavir
- Indomethacin
- Inotuzumab Ozogamicin
- Iohexol
- Iopamidol
- Iopromide
- Ioversol
- Isavuconazonium
- Isoflurane
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Isosulfan Blue
- Isradipine
- Itraconazole
- Ivabradine
- Ivacaftor
- Ivosidenib
- Ixabepilone
- Ketamine
- Ketoconazole
- Labetalol
- Lacosamide
- Lamivudine; Tenofovir Disoproxil Fumarate
- Lansoprazole; Naproxen
- Lapatinib
- Ledipasvir; Sofosbuvir
- Lefamulin
- Lemborexant
- Lenvatinib
- Lesinurad
- Lesinurad; Allopurinol
- Letermovir
- Leuprolide
- Leuprolide; Norethindrone
- Levalbuterol
- Levobunolol
- Levofloxacin
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Lidocaine
- Lidocaine; Prilocaine
- Liothyronine
- Lithium
- Lofexidine
- Lomitapide
- Long-acting beta-agonists
- Loperamide
- Loperamide; Simethicone
- Lopinavir; Ritonavir
- Lorlatinib
- Losartan
- Lovastatin
- Lovastatin; Niacin
- Lumacaftor; Ivacaftor
- Lumateperone
- Lurasidone
- Lurbinectedin
- Macimorelin
- Maprotiline
- Maraviroc
- Meclizine
- Mefloquine
- Meloxicam
- Meperidine; Promethazine
- Mesoridazine
- Mestranol; Norethindrone
- Metaproterenol
- Metformin; Repaglinide
- Metformin; Saxagliptin
- Methadone
- Methamphetamine
- Methimazole
- Methohexital
- Methyclothiazide
- Methylergonovine
- Methylprednisolone
- Metolazone
- Metoprolol
- Metronidazole
- Mexiletine
- Midazolam
- Midostaurin
- Mifepristone
- Mipomersen
- Mirtazapine
- Mitotane
- Moricizine
- Moxifloxacin
- Nadolol
- Naldemedine
- Naloxegol
- Nanoparticle Albumin-Bound Paclitaxel
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Nateglinide
- Nebivolol
- Nebivolol; Valsartan
- Nefazodone
- Nelfinavir
- Neratinib
- Nevirapine
- Niacin; Simvastatin
- Nicardipine
- Nifedipine
- Nilotinib
- Nimodipine
- Nintedanib
- Nisoldipine
- Non-Ionic Contrast Media
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olanzapine
- Olaparib
- Olodaterol
- Ombitasvir; Paritaprevir; Ritonavir
- Omeprazole; Amoxicillin; Rifabutin
- Ondansetron
- Oritavancin
- Orlistat
- Osilodrostat
- Osimertinib
- Ospemifene
- Oxaliplatin
- Oxycodone
- Ozanimod
- Paliperidone
- Panobinostat
- Paricalcitol
- Paroxetine
- Pasireotide
- Pazopanib
- Pemigatinib
- Penbutolol
- Pentamidine
- Perindopril; Amlodipine
- Perphenazine
- Perphenazine; Amitriptyline
- Pexidartinib
- Phenylephrine
- Phenylephrine; Promethazine
- Pimavanserin
- Pimozide
- Pindolol
- Pirbuterol
- Pirfenidone
- Piroxicam
- Pitolisant
- Porfimer
- Posaconazole
- Prednisolone
- Prednisone
- Primaquine
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Propofol
- Propoxyphene
- Propranolol
- Propylthiouracil, PTU
- Protriptyline
- Quazepam
- Quetiapine
- Quinidine
- Quinine
- Ramelteon
- Ranolazine
- Rasagiline
- Red Yeast Rice
- Repaglinide
- Ribociclib
- Ribociclib; Letrozole
- Rifabutin
- Rifampin
- Rifapentine
- Rifaximin
- Rilpivirine
- Riluzole
- Rimegepant
- Risperidone
- Ritonavir
- Rivaroxaban
- Rofecoxib
- Romidepsin
- Ropinirole
- Rufinamide
- Ruxolitinib
- Salmeterol
- Saquinavir
- Saxagliptin
- Segesterone Acetate; Ethinyl Estradiol
- Selpercatinib
- Selumetinib
- Sertraline
- Sevoflurane
- Short-acting beta-agonists
- Sildenafil
- Simeprevir
- Simvastatin
- Simvastatin; Sitagliptin
- Siponimod
- Sirolimus
- Sofosbuvir
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Solifenacin
- Sonidegib
- Sorafenib
- Sotalol
- St. John’s Wort, Hypericum perforatum
- Sufentanil
- Sulfonylureas
- Sunitinib
- Suvorexant
- Tacrine
- Tacrolimus
- Tadalafil
- Talazoparib
- Tamoxifen
- Tamsulosin
- Tazemetostat
- Telaprevir
- Telavancin
- Telithromycin
- Telotristat Ethyl
- Temsirolimus
- Tenofovir Alafenamide
- Tenofovir, PMPA
- Terbinafine
- Terbutaline
- Tetrabenazine
- Tezacaftor; Ivacaftor
- Thalidomide
- Theophylline, Aminophylline
- Thiazide diuretics
- Thiopental
- Thioridazine
- Thiothixene
- Thyroid hormones
- Ticagrelor
- Timolol
- Tiotropium; Olodaterol
- Tipranavir
- Tizanidine
- Tolterodine
- Tolvaptan
- Topotecan
- Toremifene
- Torsemide
- Tramadol
- Trandolapril; Verapamil
- Trazodone
- Tretinoin, ATRA
- Triamcinolone
- Triazolam
- Tricyclic antidepressants
- Trifluoperazine
- Trimipramine
- Triptorelin
- Tucatinib
- Ubrogepant
- Ulipristal
- Umeclidinium; Vilanterol
- Valdecoxib
- Vandetanib
- Vardenafil
- Vemurafenib
- Venetoclax
- Venlafaxine
- Verapamil
- Verteporfin
- Vinblastine
- Vincristine
- Vincristine Liposomal
- Vinorelbine
- Vorapaxar
- Voriconazole
- Vorinostat
- Warfarin
- Zanubrutinib
- Zileuton
- Ziprasidone
- Zolpidem
