Drugs

Prucalopride

Prucalopride Brand Name– MOTEGRITY What is Prucalopride Prucalopride is an oral selective serotonin (5HT-4) receptor agonist with enterokinetic properties. Prucalopride is approved for the treatment of chronic idiopathic constipation (CIC) in adults. The efficacy of once-daily treatment with prucalopride was evaluated in 6 double-blind, placebo-controlled, randomized, multicenter clinical studies lasting 12 weeks (5 studies) or …

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Protriptyline

Protriptyline Brand Name– Vivactil What is Protriptyline Protriptyline is a tricyclic antidepressant (TCA) of the dibenzocycloheptene type, similar to nortriptyline. Of the TCAs, protriptyline is less likely to have a sedative effect. Protriptyline is used to treat depression, especially when the depression is accompanied by apathy and withdrawal. Rarely, protriptyline is used off-label in pulmonary …

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Protamine sulfate

What is Protamine sulfate Protamine sulfate, a protein derived from fish sperm, is a chemical antagonist of heparin. Clinically, protamine is indicated for heparin overdose and is commonly used to neutralize heparin during extracorporeal circulation following dialysis, and arterial or cardiac surgery. Dosage is guided by blood coagulation studies, with each mg of protamine sulfate …

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Propylthiouracil

What is Propylthiouracil Propylthiouracil (PTU) is an oral antithyroid agent. Propylthiouracil, a thio-urea derivative, differs both chemically and structurally from methimazole, another antithyroid agent. Antithyroid agents are indicated for various hyperthyroid conditions including maintenance of a euthyroid state in patients with Graves’ disease or toxic multinodular goiter. Due to a risk for hepatotoxicity, PTU should …

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Propranolol

Propranolol Brand Names HEMANGEOL | Inderal | Inderal LA | Inderal XL | InnoPran XL What is Propranolol Propranolol is the prototype of the beta-adrenergic receptor antagonists. It is a competitive, nonselective beta-blocker without intrinsic sympathomimetic activity, similar to nadolol. Although propranolol has membrane-stabilizing effects on the action potential, these effects are clinically insignificant except in overdose situations. Propranolol …

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