What is Sulfasalazine Sulfasalazine (salicylazosulfapyridine) is a prodrug that is metabolized by intestinal bacteria to sulfapyridine and 5-aminosalicylate (5-ASA) (mesalamine). Sulfasalazine is used in the treatment of ulcerative colitis (UC), rheumatoid arthritis (RA), and juvenille idiopathic arthritis (JIA). Guidelines include the use of sulfasalazine as a conventional DMARD in selected adult patients with RA and …
What is Sulfanilamide Sulfanilamide is a topical antiinfective agent for vaginal use. It is only for the treatment of vulvovaginal candidiasis due to Candida albicans. Vaginal formulations of sulfanilamide are specially compounded to a pH approximately equal to that of the normal vagina (about 4.3). This helps to encourage growth of the normally occurring Doderlein’s bacilli. …
What is Sulfamethoxazole and Trimethoprim SMX TMP Cotrimoxazole Sulfamethoxazole; trimethoprim (also known as co-trimoxazole or TMP-SMX) is a combination product of trimethoprim and sulfamethoxazole in a fixed 1:5 ratio. This dosage ratio produces serum concentrations of 1:20, which optimize antibacterial activity against some organisms. Both trimethoprim and sulfamethoxazole are synthetic folate antagonists that are effective …
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What is Sulfamethoxazole Sulfamethoxazole is an antibacterial sulfonamide. It is classified as an intermediate-acting sulfonamide and is longer-acting than sulfisoxazole, which allows it to be given 2—3 times daily, possibly aiding in compliance. Although it was once an extremely useful antibiotic, the development of resistance and the availability of newer agents has made sulfamethoxazole almost …
What is Sulfadiazine Sulfadiazine is an oral, intermediate-duration sulfonamide antibiotic. It is used in combination with pyrimethamine for the treatment of toxoplasmosis. Sulfadiazine is also occassionally used to treat other infections due to susceptible organisms. This drug is poorly soluble in urine and causes crystalluria more often than other sulfonamides. For this reason and because …
What is Sulfacetamide and Sulfur combination medicine Sulfacetamide and sulfur are used together in a topical preparation to treat acne rosacea, acne vulgaris, and seborrheic dermatitis. Sulfacetamide is a sulfonamide antibiotic. Sulfur is a topical antimicrobial and keratolytic agent that causes a peeling and drying action. Sulfacetamide and sulfur has been historically used in dermatology …
What is Sulfacetamide Sulfacetamide is a synthetic sulfonamide antibiotic for ophthalmic or topical administration. Sulfacetamide, because it is water soluble and because a 30% solution has a pH of 7.4, is an ideal sulfonamide for ophthalmic administration. Despite the favorable pharmaceutical properties, use of sulfonamides in general has declined due to development of resistance. Sulfacetamide …