What is Zoledronic Acid Zoledronic acid (also known as zoledronate) is an intravenous (IV), heterocyclic, nitrogen-containing bisphosphonate; it is considered a third-generation bisphosphonate. Zoledronic acid is a potent inhibitor of bone resorption, making it useful in a variety of skeletal-related conditions, including hypercalcemia of malignancy, multiple myeloma, bone metastases due to solid tumors, Paget’s disease, …
What is Ziv Aflibercept Ziv aflibercept is a fully-humanized recombinant fusion protein that inhibits angiogenesis. It acts as a soluble receptor to bind vascular endothelial growth factor (VEGF)-A, VEGF-B, and placental growth factors 1 and 2 which prevents other native receptors from binding. Ziv aflibercept is indicated in combination with fluorouracil, leucovorin, and irinotecan (FOLFIRI) …
What is Ziprasidone Ziprasidone is an oral and injectable atypical antipsychotic belonging to the benzisoxazole/benzoisothiazol derivatives class. Atypical antipsychotics are first-line treatment options for the management of schizophrenia and related disorders, with the exception of clozapine. Ziprasidone has also demonstrated efficacy in adults as monotherapy for acute manic or mixed episodes associated with bipolar I …
What is the medicine Zinc Salts Zinc is a trace element. Zinc is distributed throughout the plant and animal kingdoms, second in abundance only to iron. As a trace element, zinc is essential for biologic functions and, in animals, is important in growth, appetite, testicular maturation, skin integrity, mental activity, wound healing, and immunocompetence. Zinc …
What is Zinc Oxide Zinc oxide is a topical mild astringent with weak antiseptic properties. It is used to treat dermatologic conditions such as abrasions, burns, chafing, diaper rash (diaper dermatitis), insect bites, and minor skin irritations. In the US, zinc oxide is available in a topical cream, ointment, or paste. Zinc oxide topical paste …
What is Zileuton Zileuton is an oral leukotriene modifier, specifically an inhibitor of leukotriene synthesis. Zileuton inhibits the first enzyme in the lipoxygenase pathway, 5-lipoxygenase, and thereby limits the formation of potent leukotrienes (LTB4, LTC4, LTD4, and LTE4) which are implicated in the complicated inflammatory response that occurs in certain disease states. Zileuton is indicated …
What is Zidovudine ZDV Zidovudine is an antiretroviral nucleoside reverse transcriptase inhibitor (NRTI). It is FDA-approved for the treatment of HIV-1 infections and prevention of perinatal maternal-to-fetal HIV-1 transmission (i.e., antepartum and intrapartum therapy in infected mother, postpartum therapy in exposed neonate). Due to the development of resistance, zidovudine is not recommended to be given …