Drugs

Ritodrine

What is Ritodrine This drug is discontinued in the US. Ritodrine hydrochloride is a beta-sympathomimetic amine. It is used to prolong gestation in patients with premature regular uterine contractions, occurring between weeks 20 – 36 of pregnancy. Ritodrine is very similar to terbutaline in mechanism of action, but ritodrine is the only beta2-agonist approved for …

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Risperidone

What is Risperidone Risperidone is an atypical antipsychotic of the benzisoxazole class. Atypical antipsychotics such as risperidone are first-line treatment options for the management of schizophrenia and related disorders, with the exception of clozapine. Risperidone is used clinically in adults for schizophrenia and acute manic or mixed episodes associated with bipolar I disorder, as monotherapy …

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Risedronate

What is Risedronate Risedronate is a potent oral second-generation pyridinyl bisphosphonate; it differs structurally from other available bisphosphonates due to the pyridinyl side chain shielding the active amino group. Monthly, weekly, or daily regimens are available for selected conditions. Treatment with risedronate is associated with significant increases in bone mineral density (BMD) and reduces the …

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Risankizumab

What is Risankizumab Risankizumab, an interleukin-23 antagonist, is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. Treatment with risankizumab may increase the risk of infections. Caution is advised when administering the drug to patients with a history of chronic or recurrent infections. Prior …

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Ripretinib

What is Ripretinib Ripretinib is a tyrosine kinase inhibitor that works in many mutant KIT and PDGFRA kinases found in tumor cells. It is indicated for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. Cardiac dysfunction (e.g., decreased ejection …

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Riociguat

What is Riociguat Riociguat is an oral soluble guanylate cyclase stimulator and is indicated for the treatment of adults with pulmonary arterial hypertension (PAH) (WHO group I) and patients with persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) (WHO Group 4) after surgical treatment or inoperable CTEPH. Riociguat is the first FDA-approved soluble guanylate cyclase stimulator to …

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Rimexolone

What is Rimexolone Rimexolone is a corticosteroid that is administered topically to the eye to reduce inflammation during the postoperative period following ocular surgery. It is the first ophthalmic steroid indicated for this condition. Rimexolone is also indicated for the treatment of anterior uveitis. In clinical studies, 1% rimexolone demonstrated clinical equivalence to 1% prednisolone …

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