What is Tamsulosin Tamsulosin is an oral alpha-blocker that can be administered once-daily for the treatment of benign prostatic hyperplasia (BPH). Tamsulosin appears to cause less hypotension than other alpha-blockers due to enhanced specificity for the alpha-receptors on the prostate. As a result, tamsulosin therapy can be initiated at the optimum dose whereas other alpha-blockers …
What is Tamoxifen Tamoxifen is an oral selective estrogen receptor modulator (SERM), which has both estrogenic and antiestrogenic effects on various tissues. It competes with estrogen for binding to the estrogen receptor, which can decrease estrogen receptor signaling-dependent growth in breast tissue. It is approved for the adjuvant treatment of breast cancer and for the …
What is Talimogene Laherparepvec Talimogene laherparepvec (Imlygic; T-VEC) is a live, attenuated HSV-1 that has been genetically modified to express human GM-CSF, indicated for the local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with melanoma recurrent after initial surgery. In a multicenter, randomized, open-label clinical trial, the primary outcome of durable response …
What is Taliglucerase Alfa Taliglucerase alfa is an enzyme used in the treatment of patients with Gaucher’s disease. Taliglucerase alfa replaces the endogenous enzyme beta-glucocerebrosidase. Taliglucerase alfa is produced by recombinant DNA technology using plant cell culture (carrot), making it the first plant-made pharmaceutical. This process is beneficial because it eliminates the threat of viruses …
What is Magnesium Silicate Magnesium silicate, is a respiratory agent used for the treatment of recurrent malignant pleural effusions in symptomatic patients. The composition of sterile talc products is >= 95% hydrated magnesium silicate. Associated naturally occurring minerals include chlorite (hydrated aluminum and magnesium silicate), dolomite (calcium and magnesium carbonate), calcite (calcium carbonate), and quartz. …
What is Talazoparib Talazoparib is an oral poly (ADP-ribose) polymerase (PARP) inhibitor approved for the treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), HER2-negative locally advanced or metastatic breast cancer. Treatment with talazoparib significantly improved progression-free survival compared with investigator’s choice of chemotherapy in an open-label clinical trial of patients with …
What is Tagraxofusp Tagraxofusp-erzs is a CD123-directed cytotoxin that is indicated for the treatment of blastic plasmacytoid dendritic cell neoplasm in adult and pediatric patients 2 years of age and older. Capillary leak syndrome has been reported with tagraxofusp therapy Brand Name ELZONRIS Indications blastic plasmacytoid dendritic cell neoplasm Side Effects anemia anorexia antibody formation …