What is Terbutaline Terbutaline is an oral and parenteral bronchodilator and is a systemic short-acting beta-2 adrenergic agonist (SABA); it is generally shorter acting than albuterol when given by inhalation. Clinically, its main use is for the treatment of bronchospasm. Terbutaline has also been used historically off-label for delaying premature labor; however, the FDA warned …
What is Terbinafine Terbinafine is an oral and topical antifungal agent that is pharmacologically similar to naftifine. Oral terbinafine is highly effective for treating onychomycosis due to its fungicidal activity and ability to concentrate within the nail. In clinical studies, the efficacy of oral terbinafine in the treatment of onychomycosis was found to be superior …
What is Terazosin Terazosin is an alpha-adrenergic blocking agent used in the treatment of hypertension and benign prostatic hypertrophy (BPH). It is classified as a quinazoline and is similar to doxazosin and prazosin. The duration of action of terazosin is longer than that of prazosin but shorter than that of doxazosin. In a head-to-head comparison …
What is Teprotumumab Teprotumumab is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor approved for the treatment of thyroid eye disease. It is given via intravenous infusion every 3 weeks for a total of 8 doses. Teprotumumab may cause infusion-related reactions, hyperglycemia, and exacerbation of inflammatory bowel disease. In utero exposure to teprotumumab may cause …
What is Tenofovir (PMPA) Tenofovir (also known as PMPA) is an acyclic nucleotide analog and is available as an ester prodrug, tenofovir disoproxil fumarate (tenofovir DF). Tenofovir exhibits activity against HIV-1 viruses with reduced sensitivity to nucleoside reverse transcriptase inhibitors (NRTIs), protease inhibitors (PIs), and non-nucleoside reverse transcriptase inhibitors (NNRTIs). Tenofovir’s activity is additive or …
What is Tenofovir Alafenamide Tenofovir alafenamide is a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor. It is indicated for the treatment of chronic HBV infection in adults with compensated liver disease. Similar to tenofovir disoproxil fumarate, the FDA-approved package labeling for tenofovir alafenamide contains a Black Box Warning regarding the potential for acute …
What is Teniposide Teniposide is a cytotoxic drug that is a topoisomerase II inhibitor. It is indicated in combination with other chemotherapy for induction therapy in patients with refractory acute lymphocytic leukemia. Severe myelosuppression and hypersensitivity reactions have occurred with teniposide therapy Brand Name Vumon Indications acute lymphocytic leukemia (ALL) bladder cancer neuroblastoma non-Hodgkin’s lymphoma …