Anakinra Brand Name– Kineret What is Anakinra Anakinra is a recombinant, non-glycosylated form of the human interleukin-1 receptor antagonist (IL-1Ra). The drug is produced by recombinant DNA technology using an E. coli bacterial expression system. Anakinra is useful for treating rheumatoid arthritis (RA) and some other inflammatory conditions. In adults with moderately to severely active RA, anakinra …
Anagrelide Brand Name– Agrylin What is Anagrelide Anagrelide is an oral platelet reducing agent indicated for the treatment of thrombocythemia, secondary to myeloproliferative neoplasms, to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated symptoms including thrombo-hemorrhagic events. Anagrelide therapy requires clinical monitoring, including complete blood counts, hepatic and renal …
What is Amyl Nitrite Amyl nitrite is a volatile liquid that is administered via inhalation. Its vasodilatory activity makes it useful for the pharmacologic management of angina pectoris and as a diagnostic aid for cardiovascular function. Amyl nitrite is also useful in the initial treatment of cyanide poisoning until intravenous sodium nitrite is available. Amyl …
Amprenavir Brand Name– Agenerase What is Amprenavir NOTE: This drug is discontinued in the US. Amprenavir is an HIV protease inhibitor similar to indinavir and ritonavir. Preliminary phase III data showed, in an as-treated analysis, that 88% of HIV-infected patients who received amprenavir, lamivudine, and zidovudine for 16 weeks achieved viral loads below the limit …
Ampicillin and Sulbactam Brand Name– Unasyn What is Ampicillin and Sulbactam Unasyn(R) is a parenteral antibiotic that combines ampicillin with sulbactam, a beta-lactamase inhibitor. The antimicrobial coverage of Unasyn is similar to the oral agent Augmentin(R) (see Amoxicillin; Clavulanic Acid monograph). Sulbactam alone has weak antibacterial activity. In combination with sulbactam, ampicillin’s spectrum is broadened …
Ampicillin Brand Name– Principen What is Ampicillin Ampicillin is classified as an aminopenicillin. The aminopenicillins, a group that includes amoxicillin, are able to penetrate gram-negative bacteria more readily than are the natural penicillins or penicillinase-resistant penicillins. However, the aminopenicillins are not stable to beta-lactamases of either gram-positive or gram-negative bacteria. In combination with sulbactam (a …
Amphotericin B liposomal Brand Name– AmBisome What is Amphotericin B liposomal Amphotericin B is a polyene antifungal first isolated in 1955 from Streptomyces nodosus. In 1957, amphotericin B was approved for the treatment of progressive and potentially life threatening fungal infections. Amphotericin B maintains a broad spectrum of activity with a low potential for resistance, yet …