Aprepitant Fosaprepitant Brand Names- CINVANTI / Emend What is Aprepitant Fosaprepitant Aprepitant fosaprepitant an antiemetic, is a highly selective substance P neurokinin 1 (NK1) receptor antagonist. Aprepitant is available in oral and intravenous formulations; fosaprepitant, the prodrug of aprepitant, is only available as an intravenous formulation. Aprepitant (oral and IV) and injectable fosaprepitant are approved for …
Apremilast Brand Name– Otezla What is Apremilast Apremilast is an oral phosphodiesterase-4 (PDE4) inhibitor and is considered a targeted synthetic DMARD (tsDMARD). The drug is indicated for use in adults oral ulcers associated with Behcet’s Disease, moderate-to-severe plaque psoriasis in patients who are candidates for phototherapy or systemic therapy, and for adults with active psoriatic …
Apraclonidine Brand Name– Iopidine What is Apraclonidine Apraclonidine, a relatively selective alpha2-adrenergic agonist related to clonidine, is an ophthalmic sympathomimetic agent. The 1% solution is used to control or prevent postsurgical elevation of intraocular pressure (IOP). Apraclonidine 0.5% is also used as a short-term adjunctive agent to reduce IOP in glaucoma patients receiving maximally tolerated …
Apomorphine Brand Name– Apokyn What is Apomorphine Apomorphine, a non-narcotic derivative of morphine, was first synthesized in 1869. Due to its potent emetic effects, apomorphine was used to treat acute poisonings in the early 1930s; however, safer alternatives (e.g., ipecac syrup) eventually became available. In 1951 the drug was found beneficial in the treatment of …
Apixaban Brand Name– Eliquis What is Apixaban Apixaban is an oral and selective factor Xa inhibitor anticoagulant indicated for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, for prevention of deep vein thrombosis (DVT) after hip or knee replacement surgery, for the treatment of DVT and pulmonary embolism (PE), and …
Apalutamide Brand Name– ERLEADA What is Apalutamide Apalutamide is an androgen receptor inhibitor approved for the treatment of patients with nonmetastatic castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer. Patients treated with apalutamide experienced more falls and fractures in clinical trials than patients who received placebo; patients should be evaluated for risk and treated with …
Antithymocyte Globulin Brand Names- Atgam | Thymoglobulin What is Antithymocyte Globulin Antithymocyte globulin (ATG) is a polyclonal antibody that is used for organ transplant rejection, transplant rejection prophylaxis, and moderate to severe aplastic anemia in patients unsuitable for bone marrow transplantation. Two formulations of ATG are available, derived from either horses (Atgam) or rabbits (Thymoglobulin). Rabbit …