Axitinib Brand Name– INLYTA What is Axitinib Axitinib is an oral agent that works by inhibiting receptor tyrosine kinases, including vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, and VEGFR-3. It is approved for the treatment of advanced renal cell carcinoma (RCC) after failure of one prior systemic therapy. Progression-free survival was significantly improved with axitinib …
Axicabtagene Ciloleucel Brand Name– YESCARTA What is Axicabtagene Ciloleucel Axicabtagene ciloleucel is a chimeric antigen receptor (CAR) T-cell gene therapy. It is CD19-directed immunotherapy that works by using a patient’s own genetically altered immune cells to kill B-cell cancer cells in the blood. Axicabtagene ciloleucel is indicated for use in adult patients with relapsed or …
What is Avian Influenza A H5N1 Virus Vaccine Avian influenza A H5N1 virus vaccine is an inactivated monovalent vaccine indicated for active immunization of persons at increased risk of exposure to the H5N1 influenza virus subtype contained in the vaccine. Two vaccines have received approval from the FDA, with each containing a different viral stains. …
Avelumab Brand Name– BAVENCIO What is Avelumab Avelumab is a human IgG1 lambda monoclonal antibody that binds to the programmed death ligand-1 (PD-L1) found on T-cells and blocks the interaction of PD-L1 with PD-1 and B7.1 receptors on the tumor cell. It is indicated for the treatment of metastatic Merkel cell carcinoma, advanced renal cell …
Avatrombopag Brand Name– DOPTELET What is Avatrombopag Avatrombopag is an oral thrombopoietin (TPO) receptor agonist indicated for the treatment of thrombocytopenia in patients with chronic liver disease scheduled to undergo a medical or dental procedure or with chronic immune thrombocytopenia (ITP) who have had an insufficient response to previous treatment. TPO agonists have been associated …
Avapritinib Brand Name– AYVAKIT What is Avapritinib Avapritinib is a tyrosine kinase inhibitor targeting platelet-derived growth factor receptor alpha (PDGFRA) and PDGFRA D842 mutations as well as multiple KIT exon 11, 11/17, and 17 mutations. It is indicated for the treatment of adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) harboring a PDGFRA exon …
Avanafil Brand Name– Stendra What is Avanafil Avanafil belongs to the phosphodiesterase type 5 (PDE5) inhibitors drug class, a class of drugs commonly indicated for treatment of erectile dysfunction (ED). PDE5 inhibitors do not inhibit prostaglandins as do some agents for treating impotence (e.g., alprostadil). The safety and efficacy of avanafil was studied in three …