Brigatinib Brand Name– Alunbrig What is Brigatinib Brigatinib is a tyrosine kinase inhibitor targeting multiple kinases, including anaplastic lymphoma kinase (ALK), ROS1, insulin-like growth factor-1 receptor (IGF-1R), and FLT-3, as well as EGFR deletion and point mutations. It is FDA approved for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung …
Brexpiprazole Brand Name– REXULTI What is Brexpiprazole Brexpiprazole is in an atypical antipsychotic drug subclass known as ‘dopamine system stabilizers’ (DSSs). Similar to aripiprazole, brexpiprazole is a partial dopamine agonist, which is in contrast to other antipsychotic agents that are full dopamine antagonists. Atypical antipsychotics are the standard of care for schizophrenia and related disorders, …
Brexanolone Brand Name– ZULRESSO What is Brexanolone Brexanolone is a neuroactive steroid gamma-aminobutyric acid (GABA) A receptor positive modulator for the treatment of postpartum depression in adults. Brexanolone is an analog of allopregnanolone, an endogenous steroid hormone metabolite that increases during pregnancy and then declines abruptly after birth. In some women, this decline is thought …
What is Bretylium Bretylium is a parenteral Class III antiarrhythmic agent indicated for the treatment of ventricular arrhythmias. Bretylium is associated with a high incidence of hypotension, particularly in the postresuscitation setting. Bretylium was originally introduced as an antihypertensive but was abandoned because of erratic oral absorption, rapid tolerance to its antihypertensive effects, and proclivity …
Brentuximab vedotin Brand Name– ADCETRIS What is Brentuximab vedotin Brentuximab vedotin is an antibody-drug conjugate that targets CD30, a protein expressed on the surface of certain cancer cells. It is indicated as a single-agent for consolidation therapy in adult patients with high-risk classical Hodgkin lymphoma (cHL) and for the treatment of adult patients with relapsed …
Bremelanotide Brand Name– VYLEESI What is Bremelanotide Bremelanotide is an injectable melanocortin receptor agonist. It is administered subcutaneously and indicated in premenopausal females for the treatment of Hypoactive Sexual Desire Disorder (HSDD), or low sexual desire. It has a unique mechanism of action that helps activate brain pathways that are involved in normal sexual responses. …
What is Botulism Immune Globulin BIG IV Botulism Immune Globulin BIG IV is an intravenous solution of purified human immunoglobulin G (IgG), with trace amounts of IgA and IgM. The product is derived from pooled adult plasma from persons immunized with pentavalent botulinium toxoid. Donors for BIG-IV are selected based on high titers of neutralizing …