Dalfampridine Brand Name-Ampyra What is Dalfampridine Dalfampridine, also known as 4-aminopyridine, is an oral potassium channel blocker indicated to improve walking in patients with multiple sclerosis (MS). Among patients with MS who could walk 25 feet in 8 to 45 seconds, more patients responded to dalfampridine than to placebo. Responders were defined as those with …
Dalbavancin Brand Name– DALVANCE What is Dalbavancin Dalbavancin is a second-generation glycopeptide antibiotic approved for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by certain susceptible bacteria like Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains) and Streptococcus pyogenes. Glycopeptides inhibit bacterial cell wall synthesis by blocking the transglycosylation step of peptidoglycan biosynthesis by interfering …
Dactinomycin Actinomycin D Brand Name– Cosmegen What is Dactinomycin Actinomycin D Dactinomycin is a cytotoxic antitumor antibiotic that is indicated for the treatment of adult and pediatric patients with Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, and testicular cancer in combination with chemotherapy. It is also indicated in postmenarchal patients with gestational trophoblastic neoplasia and in adult …
Dacomitinib Brand Name– VIZIMPRO What is Dacomitinib Dacomitinib is an oral, irreversible epidermal growth factor receptor (EGFR) kinase inhibitor indicated as monotherapy for the first-line treatment of metastatic non-small cell lung cancer (NSCLC) in patients with EGFR exon 19 deletions or exon 21 (L858R) substitution mutations. EGFR is expressed, overexpressed, or dysregulated in many cancers; …
Daclizumab Brand Names- Zenapax | ZINBRYTA What is Daclizumab Daclizumab was an immunosuppressant previously indicated for the treatment of relapsing forms of multiple sclerosis. Daclizumab was also historically used for rejection prophylaxis in renal allograft recipients and marketed under the trade name Zenapax, but this product was discontinued from marketing in 2009. Daclizumab is a humanized …
Daclatasvir Brand Name– Daklinza What is Daclatasvir Daclatasvir is an NS5A protein inhibitor approved for the treatment of genotype 1 and 3 chronic hepatitis C virus (HCV) infections in adults, including adults who have undergone liver transplantation, have decompensated cirrhosis, or are coinfected with HIV. Approval was based on the results of 3, open-label, phase …
Dacarbazine DTIC Brand Name– DTIC-Dome What is Dacarbazine DTIC Dacarbazine is a cell cycle-phase nonspecific antineoplastic drug that is believed to be an alkylating agent. Dacarbazine is unlike conventional alkylating agents such as cyclophosphamide or chlorambucil. It is used in the treatment of metastatic malignant melanoma, osteogenic sarcoma, soft-tissue sarcoma, and Hodgkin lymphoma. Dacarbazine is …