Desloratadine Brand Names- Clarinex | Clarinex RediTab What is Desloratadine Desloratadine is a non-sedating, potent, second-generation long-acting antihistamine(H1-blocker). Desloratadine is the active metabolite of loratadine, with a relative potency of 10 to 20 times that of loratadine in vitro. Both loratadine and desloratadine are non-sedating; however, desloratadine does not cause QT prolongation, even when given in doses …
Desirudin Brand Name– Iprivask What is Desirudin Desirudin is a parenteral bivalent recombinant analog of the natural thrombin inhibitor hirudin. Hirudin is secreted in the saliva of the medicinal leech, Hirudo medicinalis and has a 65-amino acid structure. Desirudin, which is expressed in yeast (Saccharomyces cerevisiae, strain TR 1456) by recombinant DNA technology, differs from natural hirudin …
Desipramine Brand Name– Norpramin What is Desipramine Desipramine is a tricyclic antidepressant (TCA) of the dibenzazepine type, and is the active metabolite of imipramine. Desipramine is used primarily for the treatment of major depressive disorder (MDD) in adults. Safety and efficacy have not been established in pediatric patients; usual dosing for adolescents (e.g., age 13 …
Desflurane Brand Name– Suprane What is Desflurane Desflurane is a non-flammable, volatile (below 22.8 degrees C), liquid general halogenated anesthetic. It is used in adults for induction and/or maintenance of anesthesia during surgery. Desflurane is not recommended for induction of anesthesia in pediatric patients because of the high incidence of cough, laryngospasm, apnea, secretion production, …
Deoxycholic Acid Brand Name– Kybella What is Deoxycholic Acid Deoxycholic acid is a cytolytic drug indicated for improvement in the appearance of moderate to severe convexity or fullness associated with submental fat in adults. Safety and efficacy have not been established for use outside of the submental area or in adolescent patients. Deoxycholic acid (Kybella) …
Denosumab Brand Names- Prolia | XGEVA What is Denosumab Denosumab is a subcutaneous fully human, highly specific, monoclonal antibody against receptor activator of nuclear factor kappa-beta ligand (RANKL). Denosumab (Prolia) is a monoclonal antibody directed against RANK-L. This interferes with the ability of osteoblasts (and other cells with RANK-L on their surface) to bind to RANK and …
Denileukin Diftitox Brand Name– Ontak What is Denileukin Diftitox Denileukin diftitox is a CD25-directed cytotoxin that is indicated for the treatment of persistent or recurrent cutaneous T-cell lymphoma in adult patients whose malignant cells express the CD25 component of the IL-2 receptor. Fatal cases of capillary leak syndrome and infusion-related reactions have been reported with …