Flumazenil Brand Name– Romazicon What is Flumazenil Flumazenil is a parenteral benzodiazepine antagonist. It is an imidazobenzodiazepine derivative. Flumazenil is used to treat benzodiazepine overdose and to reverse benzodiazepine sedation during anesthesia. Flumazenil will also antagonize the sedative actions of zolpidem and eszopiclone. Flumazenil is administered by rapid IV injection because it is highly irritating, …
Fludrocortisone Brand Name– Florinef What is Fludrocortisone Fludrocortisone is an oral synthetic adrenocortical steroid derived from the substitution of a 9alpha-fluoride on the B ring of hydrocortisone. Fluorination at this position gives rise to potent mineralocorticoid activity. Pharmacologic actions are similar to those of aldosterone, an endogenous mineralocorticoid. The sodium-retaining activity of fludrocortisone is extremely …
Fludarabine Brand Names- Fludara | Oforta What is Fludarabine Fludarabine is a purine nucleoside antineoplastic agent indicated for the treatment of adult patients with B-cell chronic lymphocytic leukemia who have not responded to or whose disease has progressed during treatment with at least 1 standard alkylating agent-containing regimen. Life-threatening or fatal autoimmune reactions (e.g., hemolytic anemia, …
Flucytosine Brand Name– Ancobon What is Flucytosine Flucytosine is an oral antifungal agent. It is a fluorinated pyrimidine that is structurally similar to both fluorouracil and floxuridine. Flucytosine is also known as 5-FC. It was approved by the FDA in 1971 and until recently was used mainly in combination with amphotericin B in the treatment …
Fluconazole Brand Name- Diflucan What is Fluconazole Fluconazole is a synthetic antifungal agent of the triazole class. It is administered orally and intravenously. The antifungal spectrum for fluconazole is broader than that of the imidazole antifungals class, which includes agents such as ketoconazole, miconazole, and clotrimazole. Fluconazole is more resistant to first-pass metabolism and has …
Fluciclovine F 18 Brand Name– Axumin What is Fluciclovine F 18 Fluciclovine F 18 is an intravenous, radioactive diagnostic agent for use with positron emission tomography (PET) to evaluate men with suspected prostate cancer recurrence. Following intravenous administration, fluciclovine F 18 is actively transported into prostate cancer cells, where peak accumulation occurs 4 to 10 …
Floxuridine Brand Name– FUDR What is Floxuridine Floxuridine is a cell cycle-phase specific antineoplastic agent used almost exclusively via hepatic artery administration to treat colon carcinoma metastatic to the liver. Floxuridine is a deoxyribonucleoside derivative of fluorouracil (5-FU). Floxuridine is preferred over 5-FU for intrahepatic administration because a greater percentage of floxuridine is removed from …