Drugs

Ivermectin (dihydroavermectin B1)

Ivermectin Brand Names Sklice | Soolantra | Stromectol What is Ivermectin Ivermectin (dihydroavermectin B1) is an antiparasitic agent of the avermectin class. Ivermectin has structural similarities to the macrolide antibiotics but lacks antibacterial activity. Avermectins are produced naturally by the actinomycete Streptomycetes avermetilis. Ivermectin lotion is used topically to treat Pediculosis capitis (head lice). Ivermectin cream is used topically for …

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Ivacaftor

Ivacaftor Brand Name– KALYDECO What is Ivacaftor Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator indicated for the treatment of cystic fibrosis (CF) in patients 12 months of age and older who have one mutation in the CFTR gene that is responsive to ivacaftor. Ion channel modulators, such as ivacaftor, aim to correct the underlying …

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Ivabradine

Ivabradine Brand Name– Corlanor What is Ivabradine Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated channel blocker used in stable symptomatic heart failure. In adult patients, ivabradine is indicated to reduce the risk of hospitalization for worsening heart failure in those with symptomatic (NYHA class II or III) stable chronic reduced ejection fraction (35% or less) heart …

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Itraconazole

Itraconazole Brand Names ONMEL | Sporanox | TOLSURA What is Itraconazole Itraconazole is an oral azole antifungal agent indicated for the treatment of pulmonary and extrapulmonary blastomycosis, histoplasmosis, including chronic cavitary pulmonary disease and disseminated, nonmeningeal disease, pulmonary and extrapulmonary aspergillosis in patients who are intolerant or refractory to amphotericin B, onychomycosis of the toenail or fingernail …

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Istradefylline

Istradefylline Brand Name– NOURIANZ What is Istradefylline Istradefylline is a xanthine derivative and an oral adenosine A2A receptor antagonist. Istradefylline is approved for use as an adjuvant to levodopa-carbidopa therapy in adult patients with Parkinson’s disease (PD) experiencing ‘off’ episodes. The efficacy of istradefylline was established in 4 placebo-controlled, randomized trials. In these trials, patients …

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Isradipine

Isradipine Brand Names- DynaCirc | DynaCirc CR What is Isradipine Isradipine is a calcium-channel blocking agent of the dihydropyridine class similar to nifedipine, amlodipine, and felodipine. On a milligram-per-milligram basis, isradipine is the most potent drug of this class. Currently, isradipine is approved for the treatment of hypertension. Isradipine is longer acting than regular-release nifedipine but …

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Isoxsuprine

Isoxsuprine Brand Names- Tri Soxsuprine | Vasodilan What is Isoxsuprine Isoxsuprine is a vasodilator that acts primarily on blood vessels within skeletal muscle. It is used for cerebral and peripheral vascular insufficiency. The FDA has listed isoxsuprine as being ‘possibly effective’ for its labeled indications; the drug has been designated a Level 5 on the DESI …

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