Letrozole Brand Name– Femara What is Letrozole Letrozole is a nonsteroidal oral aromatase inhibitor. It is used in postmenopausal women for the adjuvant treatment of early breast cancer, for extended adjuvant therapy after 5 years of tamoxifen, and for the treatment of advanced breast cancer. It is also used off-label for the treatment of infertility, …
Letermovir Brand Name– Prevymis What is Letermovir Letermovir is a cytomegalovirus (CMV) DNA terminase complex inhibitor indicated for prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an allogenic hematopoietic stem cell transplant (HSCT). Prophylaxis may be administered orally or intravenously as the same dose. Dosage adjustments are required when administered with cyclosporine. Significant …
Lesinurad Allopurinol Brand Name– DUZALLO What is Lesinurad Allopurinol Lesinurad, a uricosuric agent that is an urate transporter (URAT1) inhibitor, and allopurinol, a xanthine oxidase inhibitor (XOI), are used in combination to treat hyperuricemia due to gout in patients who have not achieved target serum uric acid levels with a medically appropriate daily dose of …
Lesinurad Brand Name– ZURAMPIC What is Lesinurad Lesinurad is a uricosuric agent that is a urate transporter (URAT1) inhibitor. It is used for the adjunct treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with a xanthine oxidase inhibitor alone. Lesinurad product labeling carries a boxed warning …
What is Lercanidipine Lercanidipine is an oral calcium-channel blocker. Lercanidipine is a lipophilic dihydropyridine with vascular selectivity and a prolonged duration of action (24 hours), allowing for once daily dosing. Lercanidipine has been evaluated for use in patients with hypertension, including older hypertensives and patients with isolated systolic hypertension or coexisting diabetes mellitus. It has …
Lepirudin Brand Name– Refludan What is Lepirudin Lepirudin is a yeast-derived recombinant form of the natural anticoagulant hirudin. Natural hirudin is a 65 amino acid compound produced in trace amounts by the European medicinal leech. Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule …
Lenvatinib Brand Name– LENVIMA What is Lenvatinib Lenvatinib is an oral kinase inhibitor against vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). It also inhibits other kinases that have been implicated in angiogenesis, tumor growth, and cancer progression including fibroblast growth factor (FGF) receptors 1, 2, 3, and 4, as …