Nitrofurantoin Brand Names Furadantin | Macrobid | Macrodantin | Urotoin What is Nitrofurantoin Nitrofurantoin is a nitrofuran antibacterial agent. It is specifically used to treat urinary tract infections caused by many gram-negative and some gram-positive bacteria. Two crystalline forms are available, the microcrystalline form and the macrocrystalline form, with the latter being useful for patients who cannot tolerate the microcrystalline form. Nitrofurantoin …
Nitric Oxide Brand Name– INOmax What is Nitric Oxide Inhaled nitric oxide is a selective pulmonary vasodilator and is supplied as a gaseous blend of nitric oxide (0.8%) and nitrogen (99.2%). Nitric oxide is a colorless, almost odorless gas. In the environment, nitric oxide gas is considered an air pollutant and is formed from combustion …
Nitisinone Brand Names- NITYR | Orfadin What is Nitisinone Nitisinone inhibits the breakdown of tyrosine in patients with hereditary tyrosinemia type I (HT-1). Patients with HT-1 are deficient in fumarylacetoacetate hydrolase (FAH), the final enzyme in the tyrosine catabolism pathway. Fewer than 100 children in the US are affected by this condition. Nitisinone was originally developed …
Nitazoxanide Brand Name– Alinia What is Nitazoxanide Nitazoxanide is an oral synthetic antiprotozoal agent for the treatment of cryptosporidiosis or giardiasis. In the US, the most common causes of cryptosporidiosis and giardiasis are Cryptosporidium parvum and Giardia lamblia, respectively. Nitazoxanide is the first drug specifically approved for the treatment of cryptosporidiosis. In current guidelines for managing infectious diarrhea, …
Nisoldipine Brand Name– Sular What is Nisoldipine Nisoldipine is a long-acting, oral, dihydropyridine calcium-channel blocker that is structurally related to nifedipine. In comparison with nifedipine, nisoldipine has greater affinity and selectivity for vascular smooth muscle, produces 5—10 times greater peripheral vasodilation, and has a longer elimination half-life. In comparative studies of mild to moderate hypertension, …
Niraparib Brand Name– ZEJULA What is Niraparib Niraparib is an oral poly (ADP-ribose) polymerase (PARP) inhibitor. PARP enzymes are involved in normal cellular homeostasis, including DNA transcription, cell cycle regulation, and DNA repair. It is indicated as maintenance therapy in patients with platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancer, as well as monotherapy …
Nintedanib Brand Name– Ofev What is Nintedanib Nintedanib is a kinase inhibitor that blocks multiple pathways involved in the scarring of lung tissue. The drug is approved for the treatment of adults with idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and to slow the rate of decline in …