Pegaspargase Brand Name– Oncaspar What is Pegaspargase Pegaspargase is an asparagine specific enzyme that is indicated for the first-line treatment of acute lymphoblastic leukemia (ALL) in adults and pediatric patients and ALL in adults and pediatric patients who experienced hypersensitivity to native forms of L-asparaginase. It is used in combination with multi-agent chemotherapy. Use of …
Pegaptanib Brand Name– Macugen What is Pegaptanib Pegaptanib is an aptamer, a pegylated modified oligonucleotide, that is a selective vascular endothelial growth factor (VEGF) antagonist, a type of signal-transduction inhibitor (STI) and angiogenesis inhibitor. The agent is a novel intravitreal injection for age-related macular degeneration (AMD), a leading form of blindness. The drug works by …
Pegademase Bovine Brand Name– Adagen What is Pegademase Bovine Pegademase bovine is parenteral enzyme replacement therapy for patients with severe combined immunodeficiency disease (SCID) associated with adenosine deaminase (ADA) deficiency. It is a conjugate of multiple strands of monomethoxypolyethylene glycol attached to ADA derived from bovine intestine. SCID associated with ADA deficiency is a rare, …
Peanut Arachis hypogaea Allergen Powder Brand Name-Palforzia What is Peanut Arachis hypogaea Allergen Powder Peanut Arachis hypogaea Allergen Powder is an oral immunotherapy approved for the mitigation of allergic reactions, including anaphylaxis, due to accidental exposure to peanut in patients 4 years of age and older with a confirmed peanut allergy. It cannot be used …
Pazopanib Brand Name– Votrient What is Pazopanib Pazopanib (Votrient) is an oral multikinase angiogenesis inhibitor. It targets the vascular endothelial growth factor receptor (VEGFR)-1, VEGFR-2, and VEGFR-3; platelet-derived growth factor (PDGF) receptor; fibroblast growth factor receptor (FGFR)-1 and FGFR-3; cytokine receptor (Kit); interleukin-2 receptor inducible T-cell kinase; leukocyte-specific protein tyrosine kinase; and transmembrane glycoprotein receptor …
Patisiran Brand Name– ONPATTRO What is Patisiran Patisiran is a parenteral small interfering ribonucleic acid (siRNA) indicated for the treatment of peripheral nerve disease (polyneuropathy) due to hereditary transthyretin-mediated amyloidosis (hATTR) in adults. In a randomized, placebo-controlled trial, patisiran-treated patients experienced significantly greater improvements in the modified Neuropathy Impairment Score +7 (mNIS+7) and the Quality …
Patiromer Brand Name– Veltassa What is Patiromer Patiromer is an oral potassium binder indicated for the treatment of hyperkalemia. Patiromer is not appropriate for rapid correction of life-threatening hyperkalemia because of its delayed onset of action. Patiromer binds many orally administered drugs and could result in decreased gastrointestinal absorption and loss of efficacy of the …