Pegvaliase Brand Name– PALYNZIQ What is Pegvaliase Pegvaliase is a novel subcutaneous treatment used for the treatment of phenylketonuria (PKU) in adults who have uncontrolled blood phenylalanine (Phe) concentrations greater than 600 micromol/L despite current management strategies, such as medical foods and phenylalanine-restricted diets. In the PRISM phase 3 studies, mean (SD) blood Phe was …
Pegloticase Brand Name– Krystexxa What is Pegloticase Pegloticase is a parenteral, pegylated, recombinant mammalian urate oxidase enzyme. Although the enzyme is present in most mammals, it is not found naturally in humans. The novel mechanism of action of the drug lowers uric acid concentrations by converting uric acid into allantoin, which is a benign metabolite …
Peginterferon beta 1a Brand Name– PLEGRIDY What is Peginterferon beta 1a Peginterferon beta 1a is available through recombinant DNA technology. The drug is an amino acid glycoprotein that is covalently conjugated with a methoxy polyethylene glycol (PEG) molecule, which reduces clearance in vivo allowing for a more flexible dosing schedule when compared to interferon beta-1a products. Peginterferon …
Peginterferon Alfa 2b Brand Names- PegIntron | SYLATRON What is Peginterferon Alfa 2b Peginterferon alfa 2b is a covalent conjugate of recombinant interferon alfa-2b with monomethoxy polyethylene glycol (PEG). It is indicated for the treatment of chronic hepatitis C virus infections and for the adjuvant treatment of melanoma with microscopic or gross nodal involvement within 84 …
Peginterferon Alfa 2a Brand Names Pegasys | Pegasys ProClick What is Peginterferon Alfa 2a Peginterferon alfa 2a is approved for the treatment of chronic hepatitis C virus (HCV) infections in patients 5 years and older, and for the treatment of chronic hepatitis B virus (HBV) infections in patients 3 years and older. The drug is a …
Peginesatide Brand Name– Omontys What is Peginesatide Peginesatide is an erythropoiesis-stimulating agent (ESA) for the treatment of anemia in adult dialysis patients with chronic kidney disease (CKD). In February 2013, the manufacturer instituted a voluntary recall of peginesatide after receiving post-marketing reports of serious hypersensitivity reactions including anaphylaxis and death and subsequently removed the product from …
Pegfilgrastim Brand Name– Fulphila | Neulasta | Ziextenzo What is Pegfilgrastim Pegfilgrastim is a leukocyte growth factor that binds to cell surface receptors on hematopoietic cells stimulating proliferation, differentiation, commitment, and end cell functional activation. It is indicated to increase survival in patients acutely exposed to myelosuppressive doses of radiation. Efficacy for this indication was based on …