9 Interesting Facts of Major depressive disorder Major depressive disorder is a chronic and relapsing disease, characterized by a pervasive sad mood and the loss of pleasure in most activities (anhedonia) Rule out underlying physical illnesses that may mimic major depressive disorder (eg, hypothyroidism, dementia) Diagnosis relies on history and physical examination, as well as …
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Features of pseudodementia with depression What features are characteristic of pseudodementia associated with depression? Patients with pseudodementia may or may not have a history of depressive or vegetative symptoms. They tend to have flat affect, to give up easily when mental status is examined, or to say that they cannot perform a task without even …
Cognitive deficits associated with depression What cognitive deficits are associated with depression, and what are they called? Depression is associated with deficits in episodic memory, learning and executive function, especially in set-shifting tasks. Most studies have implicated disruption of the prefrontal cortex in these impairments. Many have found that these deficits are independent of age …
Lesions commonly associated with depression What lesions are more commonly associated with depression ? Structural or functional lesions in the left anterior frontal lobe are more often associated with depression than other focal brain lesions.
New diagnostic criteria for major depressive disorder The diagnostic criteria for major depressive disorder in DSM-5 include the presence of five or more of the following symptoms during the same 2-week period: depressed mood, anhedonia, significant weight loss or weight gain, insomnia or hypersomnia, psychomotor agitation or retardation, fatigue or loss of energy, feelings of …
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Most effective treatment of Major Depressive Disorder What is the most effective treatment of MDD? What are the treatment options? Electroconvulsive therapy (ECT) is by far the most effective treatment of MDD, especially MDD with psychotic features. Other interventions include lifestyle modifications (e.g., improved sleep hygiene, diet, and exercise), psychotherapy (e.g., CBT), and pharmacotherapy (e.g., …
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How is depression distinguished from apathy dementia delirium? Apathy (indifference or lack of concern) is not depression (a persistently low mood) but may be a feature of depression. Depression is often comorbid with dementia and may itself cause cognitive problems (“pseudodementia”), but again a persistently low mood is not characteristic of dementia. Hypoactive delirium can …
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