Which common types of cancer cause inflammatory pain

Which common types of cancer cause inflammatory pain?

Commonly occurring cancers such as prostate, breast, and lung frequently metastasize to bone. Bone metastases cause painful pathological and/or compression fractures; the metastatic lesions themselves can incite significant pain due to the release of pain-signaling substances such as prostaglandins, endothelins, and bradykinin. Gastrointestinal malignancies such as colon, pancreatic, and hepatocellular carcinoma can progress to increased tumor burden; the resulting abdominal pain may be due to ascites, visceral capsular stretching, and/or extrinsic pressure on intraabdominal structures. Central nervous system tumors typically cause headache, visual pain, and/or blindness, and possible loss of sensory or motor function.


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