Hyperthyroidism in Neonates

Hyperthyroidism in Neonates

  1. Neonatal disease is usually secondary to transplacental passage of maternal TSH receptor antibodies from maternal Graves disease 
  2. May present similarly with irritability, sleep difficulty, hyperexcitability, tremors, feeding difficulty, diarrhea, and sweating
  3. Presence of goiter, small fontanelle, craniosynostosis, advanced bone age, persistent tachycardia, or proptosis with stare suggests neonatal hyperthyroidism
  4. Differentiate and diagnose neonatal hyperthyroidism with thyroid function testing
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