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What is topographagnosia and where is the lesion responsible for it?
Topographagnosia is the inability to navigate complex spatial layouts, such as a city, a building, or even one’s home, and to describe verbally or with a map how to get to a specific place or room.
This difficulty is often combined with some degree of unilateral neglect. It can be seen in right occipitoparietal damage or in bilateral temporoparietal lesions, damaging the “parahippocampal place area (PPA).”
Spatial orientation can also be disturbed in memory disorders and bilateral lesions of the visual system.
Sources
- Heilman KM: Apraxia. Continuum Lifelong Learning Neurol 16(4):86-108, 2010.
- Heilman KM, Valenstein E (eds): Clinical neuropsychology, ed 5. New York: Oxford University Press, 2011.
- Mesulam MM: Behavioral neuroanatomy. In Mesulam MM (ed): Principles of behavioral and cognitive neurology, ed 2. New York: Oxford University Press, pp. 1-120, 2000.
- Watson RT, Heilman KM: Callosal apraxia. Brain 106(Part 2):391-403, 1983.
