Why organs from an individual with blood type A2 or A2B can be transplanted into a blood type B recipient?
A2 kidneys and A2B kidneys express little A antigen on their surface. If the potential candidate has a low anti-A Ag IgG titer (<4), they are able to receive an A2 or A2B kidney transplant. If the titer is high, then the candidate can only be eligible for a kidney from a donor with a B blood type. This allows for greater access to deceased donor kidneys for those with blood type B. This strategy is not limited to deceased donor kidney transplantation, but can also be used in living donor kidney transplantation.
