Why is hyperoxaluria important in nephrolithiasis

Why is hyperoxaluria important in nephrolithiasis?

Oxalate is a significant component of the most commonly formed stones (calcium oxalate) and contributes to urine supersaturation. Previously, it was believed to be a much stronger stimulus to calcium oxalate stone formation compared with calcium. Newer data suggest that calcium may be just as potent; however, a high urinary concentration of either calcium or oxalate is a potent stimulus for calcium oxalate stone formation.


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