Which intestinal polyposis syndromes are associated with hamartomatous polyps

Which intestinal polyposis syndromes are associated with hamartomatous polyps?

  • Peutz-Jeghers syndrome (PJS)
  • Juvenile polyposis (familial or generalized)
  • Cronkhite-Canada syndrome (hamartomatous polyps with alopecia, cutaneous pigmentation, and toenail and fingernail atrophy)
  • Intestinal ganglioneuromatosis (isolated or with von Recklinghausen disease or multiple endocrine neoplasia type 2)
  • Ruvalcaba-Myhre-Smith syndrome (polyps of colon and tongue, macrocephaly, retardation, unique facies, pigmented penile macules)
  • Cowden disease (gastrointestinal [GI] polyps with oral and cutaneous verrucous papules [tricholemmomas], associated with breast cancer, thyroid neoplasia, and ovarian cysts)
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