Which endocrine diseases may cause coma?
Coma is a rare and life-threatening complication of both hypothyroidism and hyperthyroidism.
In the latter case, coma is almost always associated with thyroid storm. Decompensated hypothyroidism can cause myxedema coma, with mortality rates as high as 25% to 60%.
Coma is also found in hyperparathyroidism when serum calcium is greater than 19 mg/dL, in adrenal hypofunction with severe hyponatremia, and in DM associated with severe hyperglycemia as well as with therapy-related hypoglycemia.