Which drugs induces neuromuscular disorders?
Peripheral neuropathy
- Antimicrobial (isoniazid, ethambutol, dapsone, fluoroquinolones, metronidazole, antiretrovirals)
- Antineoplastic (vinca alkaloids, platinum analogs, taxanes, sorafenib, thalidomide)
- Antirheumatic (chloroquine, gold treatment, d -penicillamine)
- Cardiovascular (amiodarone)
- Other: colchicine
Neuromuscular junction (∗ aggravation or unmasking of myasthenia gravis)
- Antimicrobial (aminoglycosides, fluoroquinolones, telithromycin)∗
- Anticonvulsants (phenytoin)
- Antirheumatic ( d -penicillamine, chloroquine)
- Cardiovascular (quinidine, propranolol)∗
- Psychotropic (lithium, chlorpromazine)∗
- Muscle relaxants∗
Muscle (rhabdomyolysis,∗ neuroleptic malignant syndrome,∗∗ cramps/myalgias, † myopathy ‡ )
- Amphotericin B∗
- Antirheumatic (gold, † d -penicillamine, † steroid∗)
- Psychotropic (lithium,∗ haloperidol,∗∗ fluphenazine∗∗)
- Sedatives (barbiturates, diazepam)∗
- Analgesics (heroin, morphine, salicylates, codeine)∗
- Cardiovascular (statins, ‡ clofibrate,∗ labetalol, † captopril † )
- Anesthetics (suxamethonium∗)
