Which clinical characteristics increase the risk of CRC in patients with UC and Crohn’s disease?
In patients with UC and Crohn’s disease, the risk of CRC increases with:
- Longer duration
- More extensive or severe colitis (more than one-third colonic involvement)
- Family history of CRC
- Young age at onset of disease
- Presence of backwash ileitis
- Personal history of primary sclerosing cholangitis.
The presence of isolated proctitis alone does not increase the risk for CRC.
