Which anticoagulants can be used during the plasmapheresis procedure?
The most common anticoagulants used are sodium citrate, unfractionated heparin, and hirudin; nafamostat mesylate, a synthetic serine protease inhibitor, has been commonly used in Japan as an anticoagulant in hemodialysis and plasmapheresis procedures.
There are some reports of plasmapheresis without anticoagulation as a safe and effective procedure in patients at high risk of bleeding.
