What studies are used to localize a pheochromocytoma

What studies are used to localize a pheochromocytoma?

Imaging studies are generally indicated only after biochemical screening is positive. Using a scan as a screening test increases the risk of discovering an “incidentaloma” (i.e., a nonfunctioning tumor).

CT scan or MRI of the abdomen is about 95% sensitive and 65% specific; the T2-weighted MRI has a higher specificity because chromaffin tumors usually “light up.” 123 I-metaiodobenzylguanidine (MIBG) scintigraphy is about 80% sensitive and 99% specific for chromaffin tissue; it is usually used for large (>10 cm) tumors or to evaluate extra-adrenal tumors.

When imaging studies are equivocal, somatostatin receptor imaging, positron emission scanning, or even selective venous sampling of the vena cava at various levels can help locate the tumor.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856