What special considerations should be made in the perioperative management of patients with antiphospholipid syndrome

What special considerations should be made in the perioperative management of patients with antiphospholipid syndrome?

It is essential to minimize the amount of time without anticoagulation and avoid the use of vitamin K, which can complicate the resumption of therapeutic warfarin use. Another important concept is to minimize all aspects of Virchow’s triad (hypercoagulability, stasis, and endothelial injury). Examples of this include using external pneumatic compression devices in the operating room and postoperatively, setting the blood pressure cuffs to inflate less frequently, avoiding tourniquets, encouraging ambulation as soon as possible after surgery and limiting intravascular line placement and removing them as soon as they are no longer needed.

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