What osseous changes occur in patients with sarcoidosis?
The overall incidence of osseous sarcoid is reported in 3% to 13%, although this may be underestimated. Bony lesions are associated with chronic overlying cutaneous lesions and multiorgan involvement. The phalanges of the hands and feet are classically involved but with more frequent use of advanced imaging techniques, axial bone involvement is more commonly reported. The metacarpophalangeal joints, metacarpals, and wrists are usually spared. Typical radiographic findings include trabecular pattern, osteolysis, or cysts/punched out lesions. Bone scans, MRI, and fluorodeoxyglucose-positron emission tomography scans may detect unsuspected osseous involvement since over 50% of bony lesions are asymptomatic .
