Can sarcoidosis and other connective tissue diseases coexist? What other diseases?
Several reports have described sarcoidosis in patients with other rheumatic diseases, including systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sjögren’s syndrome, polymyositis, spondyloarthropathies, systemic vasculitis, and inclusion body myositis. However, the diagnosis of sarcoidosis and connective tissue disease must be made with caution. Sarcoidosis can mimic clinical and laboratory manifestations of other rheumatologic diseases and conversely, the connective tissue disease may cause granulomatous inflammation. Medication-induced sarcoidosis has been described following therapy with immune checkpoint inhibitors, highly active antiretroviral therapy, IFNs, and TNF-α antagonists.
