What is ROD?
ROD is the term used to describe the bone lesions associated with CKD-MBD. ROD is an alteration of bone morphology in patients with Chroinc Kidney Disease.
It represents the skeletal component of the systemic disorder CKD-MBD. It is assessed by bone histomorphometry. There are three key histologic descriptors:
• Bone turnover: normal, increased, or decreased
• Bone mineralization: normal or abnormal
• Bone volume: normal, increased, or decreased
This is referred to as the TMV (turnover, mineralization, and volume) system—with any combination of each of the descriptors possible in each specimen. The TMV classification scheme provides a clinically relevant description of the underlying bone pathology.
