What drugs have recently been added to the list of medications used in the symptomatic treatment of fibromyalgia

What drugs have recently been added to the list of medications used in the symptomatic treatment of fibromyalgia?

Although only pregabalin, milnacipran, and duloxetine have received a specific indication for use in the treatment of fibromyalgia, a number of others have recently been used in increasing volumes. These include centrally acting α 2 adrenergic agonists such as the muscle relaxant/analgesic tizanidine and the 5-HT3 antagonists such as ondansetron, granisetron, and tropisetron. Low-dose naltrexone (LDN) has been shown in a small double-blind study to be effective in fibromyalgia. It is a microglial modulator and has to be compounded.

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