What diseases produce elevated serum proteins and cause hyperviscosity states?
Neurologic symptoms may be the presenting symptoms of hyperviscosity due to paraproteinemias.
Multiple myeloma and Waldenström’s macroglobulinemia are the most common causes of increased serum viscosity.
In most cases, plasmapheresis is used in combination with corticosteroids and immunosuppressive drugs to prevent production of abnormal proteins and treat the underlying disease.