Variant forms of Alzheimers disease with an atypical clinical picture

Variant forms of Alzheimers disease with an atypical clinical picture

Are there variant forms of Alzheimers (AD) disease that present with an atypical clinical picture? 

Yes; these include:

  • Posterior cortical atrophy: presents with visuospatial and visual perceptual impairments (e.g., Balint’s syndrome: simultanagnosia, optic ataxia, and ocular apraxia); can also be associated with dementia with Lewy bodies, corticobasal (CB) syndrome, etc., rather than just Alzheimer’s pathology)
  • Limbic predominant AD: relatively selective memory impairment; tends to present later that typical AD; many similarities with primary age-related tauopathy (PART; formerly known as tangle predominant dementia )
  • Hippocampal-sparing AD: memory spared but with aphasia, apraxia, and/or visual perceptual impairment
15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856