Ultrasound appearance of a target lesion in the liver and its significance
A target lesion on US is characterized as a hepatic lesion with an echogenic center and a peripheral hypoechoic rim. This appearance has a high association with malignancy, including metastatic disease, hepatocellular carcinoma, and lymphoma.
In contrast, lesions with a reverse target appearance (an isoechoic to hypoechoic center and a hyperechoic rim) are more commonly associated with a benign etiology, such as a hemangioma.