total lesional glycolysis

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What is total lesional glycolysis (TLG)?

TLG (also called metabolic volumetric product [MVP]) is a global measure of disease burden in the body and is derived by first calculating the product of SUV and volume for each lesion and then summing these products over all lesions encountered in the body. TLG measurements are generally useful to prognosticate patient outcome and to quantitatively assess treatment response.

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