What are some clinical signs and symptoms associated with portal hypertension?
Esophageal, gastric, mesenteric, and rectal varices may bleed in response to elevated portal pressures; mortality related to the initial bleeding episode may be 20% or more. Increased sinusoidal pressure may result in ascites and hepatic hydrothorax. Hepatic encephalopathy, hepatorenal syndrome with renal dysfunction, and hepatopulmonary syndrome with hypoxemia may also be encountered.